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5NYT
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M2 G-quadruplex 20 wt% ethylene glycol
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
Authors:Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N.
Deposit date:2017-05-11
Release date:2018-04-11
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
5NYU
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M2 G-quadruplex 10 wt% PEG8000
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
Authors:Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N.
Deposit date:2017-05-11
Release date:2018-04-11
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
1C34
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SOLUTION STRUCTURE OF A QUADRUPLEX FORMING DNA AND ITS INTERMIDIATE
Descriptor: DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3')
Authors:Bolton, P.H, Marathias, V.M, Wang, K.
Deposit date:1999-07-24
Release date:1999-08-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNA.
Nucleic Acids Res., 28, 2000
1C32
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SOLUTION STRUCTURE OF A QUADRUPLEX FORMING DNA AND ITS INTERMIDIATE
Descriptor: DNA (5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3')
Authors:Bolton, P.H, Marathias, V.M, Wang, K.
Deposit date:1999-07-24
Release date:1999-08-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNA.
Nucleic Acids Res., 28, 2000
7MSV
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Solution Structure of Berberine Bound to a dGMP Fill-in G-Quadruplex in the PDGFR-b Promoter
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, BERBERINE, DNA (5'-D(*AP*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*AP*CP*A)-3')
Authors:Wang, K.B, Dickerhoff, J, Yang, D.
Deposit date:2021-05-12
Release date:2021-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of Ternary Complex of Berberine Bound to a dGMP-Fill-In Vacancy G-Quadruplex Formed in the PDGFR-beta Promoter.
J.Am.Chem.Soc., 143, 2021
1MF5
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GCATGCT Quadruplex
Descriptor: 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT HEXAMMINE(III)
Authors:Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Cardin, C.J.
Deposit date:2002-08-09
Release date:2003-02-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of the complementary quadruplex formed by d(GCATGCT) at atomic resolution
Nucleic Acids Res., 31, 2003
7WGW
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BU of 7wgw by Molmil
NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER)
Authors:Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y.
Deposit date:2021-12-29
Release date:2022-05-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J.Am.Chem.Soc., 144, 2022
6T51
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NMR structure of KRAS22RT G-quadruplex forming within KRAS promoter region at physological temperature
Descriptor: KRAS22RT, POTASSIUM ION
Authors:Marquevielle, J, Salgado, G.
Deposit date:2019-10-15
Release date:2019-10-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:1H,13C, and15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
Biomol.Nmr Assign., 12, 2018
1EMQ
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NMR OBSERVATION OF T-TETRADS IN A PARALLEL STRANDED DNA QUADRUPLEX FORMED BY SACCHAROMYCES CEREVISIAE TELOMERE REPEATS
Descriptor: DNA (5'-D(*TP*GP*GP*TP*GP*GP*C)-3')
Authors:Hosur, R.V, Patel, P.K.
Deposit date:2000-03-17
Release date:2000-04-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR observation of T-tetrads in a parallel stranded DNA quadruplex formed by Saccharomyces cerevisiae telomere repeats.
Nucleic Acids Res., 27, 1999
156D
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REFINED SOLUTION STRUCTURE OF THE DIMERIC QUADRUPLEX FORMED FROM THE OXYTRICHA TELOMERIC OLIGONUCLEOTIDE D(GGGGTTTTGGGG)
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3')
Authors:Schultze, P, Smith, F.W, Feigon, J.
Deposit date:1994-01-17
Release date:1994-04-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG).
Structure, 2, 1994
7Z9L
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Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
Authors:Ghosh, A, Trajkovski, M, Teulade-Fichou, M.P, Gabelica, V, Plavec, J.
Deposit date:2022-03-21
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation.
Angew.Chem.Int.Ed.Engl., 61, 2022
6SYK
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Guanine-rich oligonucleotide with 5'- and 3'-GC ends form G-quadruplex with A(GGGG)A hexad, GCGC- and G-quartets and two symmetric GG and AA base pair
Descriptor: GCnCG
Authors:Pavc, D, Wang, B, Spindler, L, Drevensek-Olenik, I, Plavec, J, Sket, P.
Deposit date:2019-09-30
Release date:2020-07-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:GC ends control topology of DNA G-quadruplexes and their cation-dependent assembly.
Nucleic Acids Res., 48, 2020
8Q4O
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RNA G-quadruplex from the 5'-UTR of human tyrosine kinase 2 (TYK2)
Descriptor: RNA (5'-R(*CP*GP*GP*UP*AP*GP*CP*GP*GP*GP*UP*AP*UP*GP*GP*GP*UP*CP*CP*GP*GP*GP*U)-3')
Authors:Toplishek, M, Kocman, V.
Deposit date:2023-08-07
Release date:2024-03-06
Method:SOLUTION NMR
Cite:High-Resolution Structure of RNA G-Quadruplex Containing Unique Structural Motifs Originating from the 5'-UTR of Human Tyrosine Kinase 2 (TYK2).
Acs Omega, 9, 2024
6FFR
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DNA-RNA Hybrid Quadruplex with Flipped Tetrad
Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')
Authors:Haase, L, Dickerhoff, J, Weisz, K.
Deposit date:2018-01-09
Release date:2018-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Chemistry, 24, 2018
1NYD
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Solution structure of DNA quadruplex GCGGTGGAT
Descriptor: 5'-D(*GP*CP*GP*GP*TP*GP*GP*AP*T)-3'
Authors:Webba da Silva, M.
Deposit date:2003-02-12
Release date:2004-02-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Association of DNA quadruplexes through G:C:G:C tetrads. Solution structure of d(GCGGTGGAT).
Biochemistry, 42, 2003
6TC8
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2'-F-arabinoguanosine and 2'-F-riboguanosine modified hybrid type G-quadruplex with V-loop
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GFL)P*(GF2)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Haase, L, Weisz, K.
Deposit date:2019-11-05
Release date:2020-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
6TCG
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2'-F-riboguanosine and 2'-F-arabinoguanosine modified G-quadruplex with V-loop and all-syn G-tract
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GF2)P*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Haase, L, Weisz, K.
Deposit date:2019-11-06
Release date:2020-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions.
Chem.Commun.(Camb.), 56, 2020
8JFQ
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Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop
Descriptor: 26mer-DNA
Authors:Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y.
Deposit date:2023-05-18
Release date:2023-08-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
7NTU
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X-ray structure of the complex between human alpha thrombin and two duplex/quadruplex aptamers: NU172 and HD22_27mer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD22_27mer, ...
Authors:Troisi, R, Santamaria, A, Sica, F.
Deposit date:2021-03-10
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human alpha-thrombin.
Int.J.Biol.Macromol., 181, 2021
8AAD
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Two carbons pendant pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder
Descriptor: 16,17-dimethoxy-21-(2-pyridin-4-ylethyl)-5,7-dioxa-13$l^{4}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(13),2,4(8),9,14,16,18,20-octaene, DNA TAGGGTTAGGGT, POTASSIUM ION
Authors:Ferraroni, M, Bazzicalupi, C, Gratteri, P, Papi, F.
Deposit date:2022-07-01
Release date:2022-12-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis.
Int J Mol Sci, 23, 2022
6JKN
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Crystal Structure of G-quadruplex Formed by Bromo-substituted Human Telomeric DNA
Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*(BGM)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*(BGM)P*G)-3'), POTASSIUM ION
Authors:Geng, Y, Cai, Q, Liu, C, Zhu, G.
Deposit date:2019-03-01
Release date:2019-04-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA.
Nucleic Acids Res., 47, 2019
6JCE
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NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes
Descriptor: 29-mer DNA
Authors:Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T.
Deposit date:2019-01-28
Release date:2019-07-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
5LQG
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A two-quartet G-quadruplex formed by human telomere in KCl solution at neutral pH
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
Authors:Galer, P, Wang, B, Sket, P, Plavec, J.
Deposit date:2016-08-17
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Reversible pH Switch of Two-Quartet G-Quadruplexes Formed by Human Telomere.
Angew.Chem.Int.Ed.Engl., 55, 2016
5LQH
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A two-quartet G-quadruplex formed by human telomere in KCl solution at pH 5.0
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
Authors:Galer, P, Wang, B, Sket, P, Plavec, J.
Deposit date:2016-08-17
Release date:2018-01-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Reversible pH Switch of Two-Quartet G-Quadruplexes Formed by Human Telomere.
Angew.Chem.Int.Ed.Engl., 55, 2016
6SUU
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NMR structure of KRAS32R G9T conformer G-quadruplex within KRAS promoter region
Descriptor: KRAS32R G9T, POTASSIUM ION
Authors:Marquevielle, J, Salgado, G.
Deposit date:2019-09-16
Release date:2020-02-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structure of two G-quadruplexes in equilibrium in the KRAS promoter.
Nucleic Acids Res., 48, 2020

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