7WGW
NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter
Summary for 7WGW
| Entry DOI | 10.2210/pdb7wgw/pdb |
| Descriptor | DNA (20-MER), CYCLIC GUANOSINE MONOPHOSPHATE (2 entities in total) |
| Functional Keywords | 8-oxo-7, 8-dihydroguanine, g-quadruplex, bloom syndrome protein, guanine metabolite, dna |
| Biological source | synthetic construct |
| Total number of polymer chains | 1 |
| Total formula weight | 6659.35 |
| Authors | Wang, K.B.,Liu, Y.,Li, Y.,Li, J.,Dickerhoff, J.,Yang, M.H.,Yang, D.,Kong, L.Y. (deposition date: 2021-12-29, release date: 2022-05-18, Last modification date: 2024-05-15) |
| Primary citation | Wang, K.B.,Liu, Y.,Li, Y.,Dickerhoff, J.,Li, J.,Yang, M.H.,Yang, D.,Kong, L.Y. Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter. J.Am.Chem.Soc., 144:6361-6372, 2022 Cited by PubMed: 35352895DOI: 10.1021/jacs.2c00435 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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