8JFQ

Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop

Summary for 8JFQ

• Entry DOI: 10.2210/pdb8jfq/pdb
• Descriptor: 26mer-DNA (1 entity in total)
• Functional Keywords: cancer, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 8248.30

Authors

Liu, Y.,Li, J.,Zhang, Y.,Wang, Y.,Chen, J.,Bian, Y.,Xia, Y.,Yang, M.H.,Zheng, K.,Wang, K.B.,Kong, L.Y. (deposition date: 2023-05-18, release date: 2023-08-02, Last modification date: 2024-05-15)

• Primary citation: Liu, Y.,Li, J.,Zhang, Y.,Wang, Y.,Chen, J.,Bian, Y.,Xia, Y.,Yang, M.H.,Zheng, K.,Wang, K.B.,Kong, L.Y.; Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.; J.Am.Chem.Soc., 145:16228-16237, 2023; PubMed: 37460135; DOI: 10.1021/jacs.3c05214

Experimental method

SOLUTION NMR