7Z9L
| Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex | Descriptor: | DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide | Authors: | Ghosh, A, Trajkovski, M, Teulade-Fichou, M.P, Gabelica, V, Plavec, J. | Deposit date: | 2022-03-21 | Release date: | 2022-08-31 | Last modified: | 2022-10-05 | Method: | SOLUTION NMR | Cite: | Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation. Angew.Chem.Int.Ed.Engl., 61, 2022
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8UFO
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8UFN
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4XQ0
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4XPZ
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6E20
| Crystal structure of the Dario rerio galectin-1-L2 | Descriptor: | Galectin, MAGNESIUM ION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Ghosh, A, Bianchet, M.A. | Deposit date: | 2018-07-10 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the zebrafish galectin-1-L2 and model of its interaction with the infectious hematopoietic necrosis virus (IHNV) envelope glycoprotein. Glycobiology, 29, 2019
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4RP3
| Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121) | Descriptor: | CHLORIDE ION, Disks large 1 tumor suppressor protein, FORMIC ACID, ... | Authors: | Ghosh, A, Ramagopal, U, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-10-29 | Release date: | 2014-11-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module. Biochemistry, 57, 2018
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4RP5
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4RP4
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4RQB
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4RQA
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4ESO
| Crystal structure of a putative oxidoreductase protein from Sinorhizobium meliloti 1021 in complex with NADP | Descriptor: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative oxidoreductase | Authors: | Ghosh, A, Bhoshle, R, Toro, R, Gizzi, A, Hillerich, B, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-04-23 | Release date: | 2012-05-16 | Method: | X-RAY DIFFRACTION (1.906 Å) | Cite: | Crystal structure of a putative oxidoreductase protein from Sinorhizobium meliloti 1021 in complex with NADP To be Published
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1XS7
| Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase). | Descriptor: | Beta-secretase 1, N-[(4S,5S,7R)-8-({(S)-1-[(BENZYLAMINO)OXOMETHYL]-2-METHYLPROPYL}AMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXO-OCT-4-YL]-(4S,7S)-4 -ISOPROPYL-2,5,9-TRIOXO-1-OXA-3,6,10-TRIAZACYCLOHEXADECANE-7-CARBOXAMIDE | Authors: | Ghosh, A, Devasamudram, T, Hong, L, DeZutter, C, Xu, X, Weerasena, V, Koelsch, G, Bilcer, G, Tang, J. | Deposit date: | 2004-10-18 | Release date: | 2004-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Bioorg.Med.Chem.Lett., 15, 2005
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2M2C
| Solution structure of Duplex DNA | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*CP*G)-3') | Authors: | Ghosh, A, Kar, R.K, Chatterjee, S, Bhunia, A. | Deposit date: | 2012-12-18 | Release date: | 2013-01-23 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Indolicidin targets duplex DNA: structural and mechanistic insight through a combination of spectroscopy and microscopy. Chemmedchem, 9, 2014
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1TPZ
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
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1TQ2
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
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1TQ6
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
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1TQD
| Crystal structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-17 | Release date: | 2004-09-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
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1TQ4
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
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3VC7
| Crystal Structure of a putative oxidoreductase from Sinorhizobium meliloti 1021 | Descriptor: | GLYCEROL, Putative oxidoreductase | Authors: | Ghosh, A, Bhoshle, R, Toro, R, Gizzi, A, Hillerich, B, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-01-03 | Release date: | 2012-01-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.231 Å) | Cite: | Crystal Structure of a putative oxidoreductase protein from Sinorhizobium meliloti 1021 To be Published
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3RTX
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3EF1
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3EF0
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4GID
| Structure of beta-secretase complexed with inhibitor | Descriptor: | Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | Authors: | Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S. | Deposit date: | 2012-08-08 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure. J.Med.Chem., 55, 2012
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5XES
| TK9 NMR structure in SDS micelle | Descriptor: | THR-VAL-TYR-VAL-TYR-SER-ARG-VAL-LYS | Authors: | Ghosh, A, Bhunia, A. | Deposit date: | 2017-04-05 | Release date: | 2018-04-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural insights of a self-assembling 9-residue peptide from the C-terminal tail of the SARS corona virus E-protein in DPC and SDS micelles: A combined high and low resolution spectroscopic study. Biochim Biophys Acta Biomembr, 1860, 2018
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