Crystal Structure of the L27 domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster (space group P21)

Summary for 4RP5

DescriptorDisks large 1 tumor suppressor protein, CHLORIDE ION (3 entities in total)
Functional Keywordsnysgrc, structural genomics, psi-biology, new york structural genomics research consortium, scaffolding, antitumor protein
Biological sourceDrosophila melanogaster (Fruit fly)
Cellular locationCytoplasm  P31007
Total number of polymer chains2
Total molecular weight22993.49
Ghosh, A.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2014-10-29, release date: 2014-11-26, Last modification date: 2018-03-21)
Primary citation
Ghosh, A.,Ramagopal, U.A.,Bonanno, J.B.,Brenowitz, M.,Almo, S.C.
Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.
Biochemistry, 2018
PubMed: 29261291 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.7b01074
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.214403.1%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution