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PDB: 249 results

3NKY
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BU of 3nky by Molmil
Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Descriptor: 3D polymerase, MAGNESIUM ION
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-21
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
1UVN
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BU of 1uvn by Molmil
The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex
Descriptor: 5'-R(*UP*UP*UP*UP*CP*CP)-3', CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
Deposit date:2004-01-21
Release date:2004-02-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
3NMA
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BU of 3nma by Molmil
Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase
Descriptor: 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ...
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-22
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
1UVL
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BU of 1uvl by Molmil
The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B
Descriptor: 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase
Authors:Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
Deposit date:2004-01-21
Release date:2004-02-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
1TQL
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BU of 1tql by Molmil
POLIOVIRUS POLYMERASE G1A MUTANT
Descriptor: ACETIC ACID, RNA-directed RNA polymerase
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2004-06-17
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23, 2004
1TP7
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BU of 1tp7 by Molmil
Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16
Descriptor: 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Genome polyprotein, SULFATE ION
Authors:Appleby, T.C, Luecke, H, Shim, J.H, Wu, J.Z, Cheney, I.W, Zhong, W, Vogeley, L, Hong, Z, Yao, N.
Deposit date:2004-06-15
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79, 2005
4K50
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BU of 4k50 by Molmil
Rhinovirus 16 polymerase elongation complex (r1_form)
Descriptor: ACETATE ION, GLYCEROL, RNA (33-MER), ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2013-04-12
Release date:2013-05-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4S
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BU of 4k4s by Molmil
Poliovirus polymerase elongation complex (r3_form)
Descriptor: GLYCEROL, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*GP*GP*GP*AP*GP*AP*UP*GP*A)-3'), ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2013-04-12
Release date:2013-05-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4W
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BU of 4k4w by Molmil
Poliovirus polymerase elongation complex (r5+2_form)
Descriptor: RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*AP*GP*AP*UP*GP*AP*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL
Authors:Gong, P, Peersen, O.B.
Deposit date:2013-04-12
Release date:2013-05-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4LQ9
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BU of 4lq9 by Molmil
Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2
Descriptor: MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid
Authors:Milani, M, Tarantino, D, Mastrangelo, E, Croci, R.
Deposit date:2013-07-17
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
4LQ3
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BU of 4lq3 by Molmil
Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS
Descriptor: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, 5'-R(P*GP*G)-3', MAGNESIUM ION, ...
Authors:Milani, M, Tarantino, D, Mastrangelo, E, Croci, R.
Deposit date:2013-07-17
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
4NLT
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BU of 4nlt by Molmil
Poliovirus Polymerase - S291P Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLP
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BU of 4nlp by Molmil
Poliovirus Polymerase - C290V Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLX
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BU of 4nlx by Molmil
Poliovirus Polymerase - G289A/C290V Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NZ0
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BU of 4nz0 by Molmil
The EMCV 3Dpol structure at 2.8A resolution
Descriptor: CHLORIDE ION, GLYCEROL, Genome polyprotein
Authors:Vives-adrian, L, Ferrer-orta, C, Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NLU
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BU of 4nlu by Molmil
Poliovirus Polymerase - G289A Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLS
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BU of 4nls by Molmil
Poliovirus Polymerase - S288A Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NYZ
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BU of 4nyz by Molmil
The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution
Descriptor: GLUTAMINE, GLYCEROL, Genome polyprotein, ...
Authors:Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N.
Deposit date:2013-12-11
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NLQ
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BU of 4nlq by Molmil
Poliovirus Polymerase - C290F Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4O4R
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BU of 4o4r by Molmil
Murine Norovirus RdRp in complex with PPNDS
Descriptor: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION
Authors:Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E.
Deposit date:2013-12-19
Release date:2014-11-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014
4NLV
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BU of 4nlv by Molmil
Poliovirus Polymerase - G289A/C290F Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NRT
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BU of 4nrt by Molmil
Human Norovirus polymerase bound to Compound 6 (suramin derivative)
Descriptor: 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, hNV-RdRp
Authors:Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Milani, M, Bolognesi, M.
Deposit date:2013-11-27
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4NLW
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BU of 4nlw by Molmil
Poliovirus Polymerase - G289A/C290I Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLY
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BU of 4nly by Molmil
Poliovirus Polymerase - C290E Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
4NLR
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BU of 4nlr by Molmil
Poliovirus Polymerase - C290S Loop Mutant
Descriptor: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Sholders, A.J, Peersen, O.B.
Deposit date:2013-11-14
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014

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PDB entries from 2024-08-14

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