4LQ9
Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2
Summary for 4LQ9
Entry DOI | 10.2210/pdb4lq9/pdb |
Related | 4LQ3 |
Descriptor | RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rna-dependent-rna-polymerase, rdrp-inhibotir complex, viral protein-replication inhibitor complex, viral protein/replication inhibitor |
Biological source | Norovirus |
Total number of polymer chains | 1 |
Total formula weight | 59258.66 |
Authors | Milani, M.,Tarantino, D.,Mastrangelo, E.,Croci, R. (deposition date: 2013-07-17, release date: 2014-02-12, Last modification date: 2024-02-28) |
Primary citation | Tarantino, D.,Pezzullo, M.,Mastrangelo, E.,Croci, R.,Rohayem, J.,Robel, I.,Bolognesi, M.,Milani, M. Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102:23-28, 2014 Cited by PubMed: 24316032DOI: 10.1016/j.antiviral.2013.11.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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