4LQ9
Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001172 | biological_process | RNA-templated transcription |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 21D A 601 |
| Chain | Residue |
| A | GLN414 |
| A | HOH792 |
| A | HOH948 |
| A | TRP417 |
| A | THR418 |
| A | ARG419 |
| A | HIS433 |
| A | GLN435 |
| A | ARG436 |
| A | GLN439 |
| A | ASN505 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 21D A 602 |
| Chain | Residue |
| A | TYR41 |
| A | GLN66 |
| A | VAL170 |
| A | LYS171 |
| A | LYS174 |
| A | LYS180 |
| A | ARG182 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 603 |
| Chain | Residue |
| A | ASP240 |
| A | ASP344 |
| A | GLU345 |
| A | THR389 |
| A | HOH858 |
| A | HOH862 |






