4LQ9

Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-dependent RNA-polymerase	polymer	526	58657.8	1	UniProt (Q2N379) Pfam (PF00680) In PDB	Norovirus
2	A	naphthalene-1,5-disulfonic acid	non-polymer		288.3	2	Chemie (21D)
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4		water	water		18.0	425	Chemie (HOH)

Sequence modifications

A: 3 - 510 (UniProt: Q2N379)

PDB	External Database	Details
Met 0	-	expression tag
Gly 1	-	expression tag
Gly 2	-	expression tag
Gly 153	Glu 153	conflict
Val 511	-	expression tag
Asp 512	-	expression tag
Lys 513	-	expression tag
Leu 514	-	expression tag
Ala 515	-	expression tag
Ala 516	-	expression tag
Ala 517	-	expression tag
Leu 518	-	expression tag
Glu 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	58657.8
Non-Polymers*	Number of molecules	3
	Total formula weight	600.9
All*	Total formula weight	59258.7

*Water molecules are not included.