4K4W
Poliovirus polymerase elongation complex (r5+2_form)
Summary for 4K4W
Entry DOI | 10.2210/pdb4k4w/pdb |
Related | 1RA6 3OL6 4K4S 4K4T 4K4U 4K4V 4K4X 4K4Y 4K4Z 4K50 |
Descriptor | RNA-directed RNA polymerase 3D-POL, RNA (5'-R(P*GP*GP*GP*AP*GP*AP*UP*GP*AP*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... (4 entities in total) |
Functional Keywords | polymerase, rna-dependent rna polymerase, protein-rna complex, transferase-rna complex, transferase/rna |
Biological source | Human poliovirus 1 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 |
Total number of polymer chains | 6 |
Total formula weight | 141602.79 |
Authors | Gong, P.,Peersen, O.B. (deposition date: 2013-04-12, release date: 2013-05-22, Last modification date: 2024-02-28) |
Primary citation | Gong, P.,Kortus, M.G.,Nix, J.C.,Davis, R.E.,Peersen, O.B. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8:e60272-e60272, 2013 Cited by PubMed: 23667424DOI: 10.1371/journal.pone.0060272 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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