1TP7

Crystal Structure of the RNA-dependent RNA Polymerase from Human Rhinovirus 16

Summary for 1TP7

DescriptorGenome polyprotein, SULFATE ION, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, ... (4 entities in total)
Functional Keywordsrhinovirus, rna, polymerase, 3d, transferase
Biological sourceHuman rhinovirus 16
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) Q82122
Total number of polymer chains4
Total molecular weight211893.52
Authors
Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N. (deposition date: 2004-06-15, release date: 2005-06-21, Last modification date: 2011-07-13)
Primary citation
Appleby, T.C.,Luecke, H.,Shim, J.H.,Wu, J.Z.,Cheney, I.W.,Zhong, W.,Vogeley, L.,Hong, Z.,Yao, N.
Crystal structure of complete rhinovirus RNA polymerase suggests front loading of protein primer.
J.Virol., 79:277-288, 2005
PubMed: 15596823 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.79.1.277-288.2005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers151.6%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution