1TQL
POLIOVIRUS POLYMERASE G1A MUTANT
Summary for 1TQL
Entry DOI | 10.2210/pdb1tql/pdb |
Related | 1RA6 1RA7 1RAJ |
Descriptor | RNA-directed RNA polymerase, ACETIC ACID (3 entities in total) |
Functional Keywords | nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, n-terminus, transferase |
Biological source | Human poliovirus 1 |
Cellular location | Capsid protein VP0: Virion. Capsid protein VP4: Virion. Capsid protein VP2: Virion. Capsid protein VP3: Virion. Capsid protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion. Protease 3C: Host cytoplasm. Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03300 |
Total number of polymer chains | 1 |
Total formula weight | 53362.20 |
Authors | Thompson, A.A.,Peersen, O.B. (deposition date: 2004-06-17, release date: 2004-08-17, Last modification date: 2023-08-23) |
Primary citation | Thompson, A.A.,Peersen, O.B. Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase Embo J., 23:3462-3471, 2004 Cited by PubMed: 15306852DOI: 10.1038/sj.emboj.7600357 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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