1RA6

Poliovirus Polymerase Full Length Apo Structure

Summary for 1RA6

• Entry DOI: 10.2210/pdb1ra6/pdb
• Related: 1RA7 1RAJ 1RDR 1TQL
• Descriptor: Genome polyprotein, ACETIC ACID (3 entities in total)
• Functional Keywords: nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, n-terminus, transferase
• Biological source: Human poliovirus 1
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300
• Total number of polymer chains: 1
• Total formula weight: 53468.27

Authors

Thompson, A.A.,Peersen, O.B. (deposition date: 2003-10-31, release date: 2004-08-17, Last modification date: 2023-08-23)

• Primary citation: Thompson, A.A.,Peersen, O.B.; Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.; Embo J., 23:3462-3471, 2004; PubMed: 15306852; DOI: 10.1038/sj.emboj.7600357

Experimental method

X-RAY DIFFRACTION (2 Å)