1RA6

Poliovirus Polymerase Full Length Apo Structure

Summary for 1RA6

Related1RDR 1RA7 1RAJ 1TQL
DescriptorGenome polyprotein, ACETIC ACID (3 entities in total)
Functional Keywordsnucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, n-terminus, transferase
Biological sourceHuman poliovirus 1
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) P03300
Total number of polymer chains1
Total molecular weight53468.27
Authors
Thompson, A.A.,Peersen, O.B. (deposition date: 2003-10-31, release date: 2004-08-17, Last modification date: 2011-07-13)
Primary citation
Thompson, A.A.,Peersen, O.B.
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23:3462-3471, 2004
PubMed: 15306852 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600357
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23816 0.2% 2.0% 6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02