3VWK
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5NME
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![BU of 5nme by Molmil](/molmil-images/mine/5nme) | 868 TCR in complex with HLA A02 presenting SLYNTVATL | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | Deposit date: | 2017-04-05 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
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5HHO
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![BU of 5hho by Molmil](/molmil-images/mine/5hho) | Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-G4E | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Gras, S, Josephs, T.M, Rossjohn, J. | Deposit date: | 2016-01-11 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses. Proc.Natl.Acad.Sci.USA, 113, 2016
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7S8R
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![BU of 7s8r by Molmil](/molmil-images/mine/7s8r) | Crystal Structure of HLA A*1101 in complex with SALEWIKNK, an 9-mer epitope from Influenza B | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | Authors: | Nguyen, A.T, Szeto, C, Gras, S. | Deposit date: | 2021-09-19 | Release date: | 2022-02-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people. Plos Pathog., 18, 2022
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5WKF
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![BU of 5wkf by Molmil](/molmil-images/mine/5wkf) | D30 TCR in complex with HLA-A*11:01-GTS1 | Descriptor: | Beta-2-microglobulin, D30 TCR beta chain, GTS1 peptide, ... | Authors: | Gras, S, Rossjohn, J. | Deposit date: | 2017-07-25 | Release date: | 2017-09-20 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response. Nat. Immunol., 18, 2017
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6C09
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![BU of 6c09 by Molmil](/molmil-images/mine/6c09) | Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex | Descriptor: | (2R)-2,3-dihydroxypropyl hexadecanoate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wun, K.S, Rossjohn, J. | Deposit date: | 2017-12-28 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat. Immunol., 19, 2018
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6RSY
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7JYX
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![BU of 7jyx by Molmil](/molmil-images/mine/7jyx) | Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza | Descriptor: | Beta-2-microglobulin, MHC class I antigen, PB2 peptide from Influenza, ... | Authors: | Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. | Deposit date: | 2020-09-01 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
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6AT9
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![BU of 6at9 by Molmil](/molmil-images/mine/6at9) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101 | Descriptor: | ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | Deposit date: | 2017-08-28 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.9503 Å) | Cite: | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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6DKP
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![BU of 6dkp by Molmil](/molmil-images/mine/6dkp) | The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide | Descriptor: | Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ... | Authors: | Hellman, L.M, Singh, N.K. | Deposit date: | 2018-05-30 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.966 Å) | Cite: | Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol. Ther., 27, 2019
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4X6D
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![BU of 4x6d by Molmil](/molmil-images/mine/4x6d) | CD1a ternary complex with endogenous lipids and BK6 TCR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, OLEIC ACID, ... | Authors: | Birkinshaw, R.W, Rossjohn, J. | Deposit date: | 2014-12-08 | Release date: | 2015-01-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands. Nat.Immunol., 16, 2015
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7NMF
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![BU of 7nmf by Molmil](/molmil-images/mine/7nmf) | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLN-LEU-PRO-ARG-LEU-PHE-PRO-LEU-LEU, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Cole, D.K, Wall, A. | Deposit date: | 2021-02-23 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form To Be Published
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4MJI
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![BU of 4mji by Molmil](/molmil-images/mine/4mji) | T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01 | Descriptor: | Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ... | Authors: | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M. | Deposit date: | 2013-09-03 | Release date: | 2014-05-28 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01 J.Immunol., 192, 2014
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7NDT
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![BU of 7ndt by Molmil](/molmil-images/mine/7ndt) | UL40:01 TCR in complex with HLA-E with a non-natural amino acid | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... | Authors: | Pengelly, R.J, Robinson, R.A. | Deposit date: | 2021-02-02 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.999 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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6TRO
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![BU of 6tro by Molmil](/molmil-images/mine/6tro) | Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV | Descriptor: | Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), MHC class I antigen, ... | Authors: | Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S. | Deposit date: | 2019-12-19 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. J.Biol.Chem., 295, 2020
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3HG1
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![BU of 3hg1 by Molmil](/molmil-images/mine/3hg1) | Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor | Descriptor: | Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ... | Authors: | Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K. | Deposit date: | 2009-05-13 | Release date: | 2009-07-28 | Last modified: | 2014-04-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. J.Biol.Chem., 284, 2009
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1EFX
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![BU of 1efx by Molmil](/molmil-images/mine/1efx) | STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3 | Descriptor: | BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ... | Authors: | Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D. | Deposit date: | 2000-02-10 | Release date: | 2000-06-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature, 405, 2000
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7PBE
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![BU of 7pbe by Molmil](/molmil-images/mine/7pbe) | Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-08-02 | Release date: | 2022-04-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7RYO
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![BU of 7ryo by Molmil](/molmil-images/mine/7ryo) | CD1a-dideoxymycobactin-gdTCR complex | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ... | Authors: | Wegrecki, M, Le Nours, J, Rossjohn, J. | Deposit date: | 2021-08-25 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
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4HKJ
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4QRR
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![BU of 4qrr by Molmil](/molmil-images/mine/4qrr) | Crystal Structure of HLA B*3501-IPS in complex with a Delta-Beta TCR, clone 12 TCR | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | Authors: | Gras, S, Chabrol, E, Rossjohn, J. | Deposit date: | 2014-07-02 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The molecular bases of delta / alpha beta T cell-mediated antigen recognition. J.Exp.Med., 211, 2014
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8FJA
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6VQO
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![BU of 6vqo by Molmil](/molmil-images/mine/6vqo) | T cell receptor-p53-HLA-A2 complex | Descriptor: | Beta-2-microglobulin, MHC class I antigen, T-cell receptor 1a2, ... | Authors: | Wu, D, Gallagher, D.T, Pierce, B.G, Mariuzza, R.A. | Deposit date: | 2020-02-05 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
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7T0L
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![BU of 7t0l by Molmil](/molmil-images/mine/7t0l) | |
8A7O
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![BU of 8a7o by Molmil](/molmil-images/mine/8a7o) | |