6C09

Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex

Summary for 6C09

• Entry DOI: 10.2210/pdb6c09/pdb
• Descriptor: T-cell surface glycoprotein CD1c, DI(HYDROXYETHYL)ETHER, Beta-2-microglobulin, ... (11 entities in total)
• Functional Keywords: t cell receptor, antigen presentation, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 96710.37

Authors

Wun, K.S.,Rossjohn, J. (deposition date: 2017-12-28, release date: 2018-03-21, Last modification date: 2023-10-04)

• Primary citation: Wun, K.S.,Reijneveld, J.F.,Cheng, T.Y.,Ladell, K.,Uldrich, A.P.,Le Nours, J.,Miners, K.L.,McLaren, J.E.,Grant, E.J.,Haigh, O.L.,Watkins, T.S.,Suliman, S.,Iwany, S.,Jimenez, J.,Calderon, R.,Tamara, K.L.,Leon, S.R.,Murray, M.B.,Mayfield, J.A.,Altman, J.D.,Purcell, A.W.,Miles, J.J.,Godfrey, D.I.,Gras, S.,Price, D.A.,Van Rhijn, I.,Moody, D.B.,Rossjohn, J.; T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.; Nat. Immunol., 19:397-406, 2018; PubMed: 29531339; DOI: 10.1038/s41590-018-0065-7

Experimental method

X-RAY DIFFRACTION (2.95 Å)