7JYX

Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza

Summary for 7JYX

• Entry DOI: 10.2210/pdb7jyx/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, PB2 peptide from Influenza, TYQWIIRNWET, ... (4 entities in total)
• Functional Keywords: hla a*2402, influenza virus, tcr, t cell, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 90684.60

Authors

Gras, S.,Nguyen, A.T.,Szeto, C.,Rossjohn, J. (deposition date: 2020-09-01, release date: 2021-04-14, Last modification date: 2023-10-18)

• Primary citation: Hensen, L.,Illing, P.T.,Bridie Clemens, E.,Nguyen, T.H.O.,Koutsakos, M.,van de Sandt, C.E.,Mifsud, N.A.,Nguyen, A.T.,Szeto, C.,Chua, B.Y.,Halim, H.,Rizzetto, S.,Luciani, F.,Loh, L.,Grant, E.J.,Saunders, P.M.,Brooks, A.G.,Rockman, S.,Kotsimbos, T.C.,Cheng, A.C.,Richards, M.,Westall, G.P.,Wakim, L.M.,Loudovaris, T.,Mannering, S.I.,Elliott, M.,Tangye, S.G.,Jackson, D.C.,Flanagan, K.L.,Rossjohn, J.,Gras, S.,Davies, J.,Miller, A.,Tong, S.Y.C.,Purcell, A.W.,Kedzierska, K.; CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.; Nat Commun, 12:2931-2931, 2021; PubMed: 34006841; DOI: 10.1038/s41467-021-23212-x

Experimental method

X-RAY DIFFRACTION (2.95 Å)