8A7O

beta-2-microglobulin DeltaN6 amyloid fibril form 2PFa

Summary for 8A7O

• Entry DOI: 10.2210/pdb8a7o/pdb
• EMDB information: 15222
• Descriptor: Beta-2-microglobulin form pI 5.3 (1 entity in total)
• Functional Keywords: amyloid, fibril, helical, cross-beta, dialysis-related amyloidosis, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 66920.87

Authors

Wilkinson, M.,Gallardo, R.,Radford, S.E.,Ranson, N.A. (deposition date: 2022-06-21, release date: 2023-03-22)

• Primary citation: Wilkinson, M.,Gallardo, R.U.,Martinez, R.M.,Guthertz, N.,So, M.,Aubrey, L.D.,Radford, S.E.,Ranson, N.A.; Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.; Nat Commun, 14:1190-1190, 2023; PubMed: 36864041; DOI: 10.1038/s41467-023-36791-8

Experimental method

ELECTRON MICROSCOPY (3 Å)