5NME

868 TCR in complex with HLA A02 presenting SLYNTVATL

Summary for 5NME

DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Gag protein, ... (9 entities in total)
Functional Keywordsmhc, tcr, cd8+, immune system
Biological sourceHomo sapiens (Human)
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Cellular locationMembrane; Single-pass type I membrane protein P01892
Secreted . Note=(Microbial infection) In the presence of M P61769
Total number of polymer chains10
Total molecular weight190408.42
Authors
Rizkallah, P.J.,Cole, D.K.,Fuller, A.,Sewell, A.K. (deposition date: 2017-04-05, release date: 2017-11-15, Last modification date: 2017-12-20)
Primary citation
Cole, D.K.,Fuller, A.,Dolton, G.,Zervoudi, E.,Legut, M.,Miles, K.,Blanchfield, L.,Madura, F.,Holland, C.J.,Bulek, A.M.,Bridgeman, J.S.,Miles, J.J.,Schauenburg, A.J.A.,Beck, K.,Evavold, B.D.,Rizkallah, P.J.,Sewell, A.K.
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8:1503-1503, 2017
PubMed: 29209312 (PDB entries with the same primary citation)
DOI: 10.3389/fimmu.2017.01503
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.94 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26440.6%13.5%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 5nme
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Molmil generated image of 5nme
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Molmil generated image of 5nme
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5nme.pdb1.gz [288.93 KB])
Coordinate files for Biological unit (5nme.pdb2.gz [289.34 KB])