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4GKS
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BU of 4gks by Molmil
A2-MHC Complex carrying FLTGIGIITV
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, FLT Cognate peptide, ...
Authors:Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4GKN
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BU of 4gkn by Molmil
A2-MHC Complex carrying FATGIGIITV
Descriptor: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
Authors:Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
6HBY
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BU of 6hby by Molmil
HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
Descriptor: 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ...
Authors:MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J.
Deposit date:2018-08-13
Release date:2019-08-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
J.Biol.Chem., 294, 2019
7ZUC
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BU of 7zuc by Molmil
Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ...
Authors:Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A.
Deposit date:2022-05-12
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
3O4L
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BU of 3o4l by Molmil
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BSLF2/BMLF1 protein, Beta-2-microglobulin, ...
Authors:Miles, J.J, Bulek, A.M, Cole, D.K, Gostick, E, Schauenburg, J.A, Dolton, G, Venturi, V, Davenport, M.P, Tan, M.P, Burrows, S.R, Wooldridge, L, Price, D.A, Rizkallah, P.J, Sewell, A.K.
Deposit date:2010-07-27
Release date:2011-01-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010
3UTQ
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BU of 3utq by Molmil
Human HLA-A*0201-ALWGPDPAAA
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTS
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BU of 3uts by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Monoclinic
Descriptor: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTT
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BU of 3utt by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Triclinic
Descriptor: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M, Rossjohn, J, Gras, S.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTP
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BU of 3utp by Molmil
1E6 TCR specific for HLA-A*0201-ALWGPDPAAA
Descriptor: 1E6 TCR alpha chain, 1E6 TCR beta chain, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
7Q9A
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BU of 7q9a by Molmil
MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q98
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BU of 7q98 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST
Descriptor: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Sewell, A.K.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q99
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BU of 7q99 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR
Descriptor: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q9B
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BU of 7q9b by Molmil
MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ...
Authors:Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
Deposit date:2021-11-12
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
4MNQ
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BU of 4mnq by Molmil
TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Jakobsen, B.K.
Deposit date:2013-09-11
Release date:2013-11-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.742 Å)
Cite:T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J.Biol.Chem., 289, 2014
4MJI
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BU of 4mji by Molmil
T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01
Descriptor: Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M.
Deposit date:2013-09-03
Release date:2014-05-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01
J.Immunol., 192, 2014
4QOK
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BU of 4qok by Molmil
Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2014-06-20
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.
Eur.J.Immunol., 45, 2015
5EU4
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BU of 5eu4 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU3
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BU of 5eu3 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU5
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BU of 5eu5 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU6
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BU of 5eu6 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
4U1I
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BU of 4u1i by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1H
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BU of 4u1h by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1L
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BU of 4u1l by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1K
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BU of 4u1k by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015

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PDB entries from 2024-03-13

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