6DKP

The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide

Summary for 6DKP

Entry DOI	10.2210/pdb6dkp/pdb
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Melanoma antigen recognized by T-cells 1, ... (5 entities in total)
Functional Keywords	alpha-beta t-cell receptor, class i mhc, hla-a2, mart-1 peptide, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	94076.59
Authors	Hellman, L.M.,Singh, N.K. (deposition date: 2018-05-30, release date: 2019-04-10, Last modification date: 2023-10-11)
Primary citation	Hellman, L.M.,Foley, K.C.,Singh, N.K.,Alonso, J.A.,Riley, T.P.,Devlin, J.R.,Ayres, C.M.,Keller, G.L.J.,Zhang, Y.,Vander Kooi, C.W.,Nishimura, M.I.,Baker, B.M. Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol. Ther., 27:300-313, 2019 Cited by PubMed: 30617019 DOI: 10.1016/j.ymthe.2018.12.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.966 Å)

Structure validation