6AT9
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101
Summary for 6AT9
| Entry DOI | 10.2210/pdb6at9/pdb |
| Descriptor | HLA class I histocompatibility antigen, A-1 alpha chain, Beta-2-microglobulin, ALK (3 entities in total) |
| Functional Keywords | lymphoma kinase-derived neuroblastoma tumor antigen, human major histocompatibility complex class i, mhc-i, complex, immune system |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Membrane; Single-pass type I membrane protein: P30443 Secreted . Note=(Microbial infection) In the presence of M: P61769 |
| Total number of polymer chains | 3 |
| Total formula weight | 45697.67 |
| Authors | Toor, J.,Rao, A.A.,Salama, S.,Tripathi, S.,Haussler, D.,Sgourakis, N.G. (deposition date: 2017-08-28, release date: 2018-03-21, Last modification date: 2023-10-04) |
| Primary citation | Toor, J.S.,Rao, A.A.,McShan, A.C.,Yarmarkovich, M.,Nerli, S.,Yamaguchi, K.,Madejska, A.A.,Nguyen, S.,Tripathi, S.,Maris, J.M.,Salama, S.R.,Haussler, D.,Sgourakis, N.G. A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9:99-99, 2018 Cited by PubMed: 29441070DOI: 10.3389/fimmu.2018.00099 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9503 Å) |
Structure validation
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