4MJI

T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01

Summary for 4MJI

• Entry DOI: 10.2210/pdb4mji/pdb
• Descriptor: HLA class I histocompatibility antigen, B-51 alpha chain, Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, ... (5 entities in total)
• Functional Keywords: hiv, peptide-major histocompatibility complex, pmhc, surface plasmon resonance, spr, t-cell, t-cell receptor, tcr, immunoglobulin, class i mhc, antigen presentation, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P18464; Secreted: P61769
• Total number of polymer chains: 10
• Total formula weight: 186354.04

Authors

Rizkallah, P.J.,Cole, D.K.,Sewell, A.K.,Motozono, C.,Takiguchi, M. (deposition date: 2013-09-03, release date: 2014-05-28)

• Primary citation: Motozono, C.,Kuse, N.,Sun, X.,Rizkallah, P.J.,Fuller, A.,Oka, S.,Cole, D.K.,Sewell, A.K.,Takiguchi, M.; Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01; J.Immunol., 192:3428-3434, 2014; PubMed: 24600035; DOI: 10.4049/jimmunol.1302667

Experimental method

X-RAY DIFFRACTION (2.99 Å)