8S4G
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![BU of 8s4g by Molmil](/molmil-images/mine/8s4g) | Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | Deposit date: | 2024-02-21 | Release date: | 2024-03-13 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex To Be Published
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2EC8
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![BU of 2ec8 by Molmil](/molmil-images/mine/2ec8) | Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | Deposit date: | 2007-02-11 | Release date: | 2007-08-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130, 2007
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2ASQ
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![BU of 2asq by Molmil](/molmil-images/mine/2asq) | Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM) | Descriptor: | Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1 | Authors: | Song, J, Zhang, Z, Hu, W, Chen, Y. | Deposit date: | 2005-08-23 | Release date: | 2005-10-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation J.Biol.Chem., 280, 2005
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2E9W
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![BU of 2e9w by Molmil](/molmil-images/mine/2e9w) | Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | Deposit date: | 2007-01-27 | Release date: | 2007-08-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor Cell(Cambridge,Mass.), 130, 2007
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6LSA
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![BU of 6lsa by Molmil](/molmil-images/mine/6lsa) | Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | Deposit date: | 2020-01-17 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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4E57
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![BU of 4e57 by Molmil](/molmil-images/mine/4e57) | |
6LS9
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![BU of 6ls9 by Molmil](/molmil-images/mine/6ls9) | Crystal structure of bovine herpesvirus 1 glycoprotein D | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | Deposit date: | 2020-01-17 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor. Sci Adv, 6, 2020
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6IWK
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![BU of 6iwk by Molmil](/molmil-images/mine/6iwk) | The Structure of Maltooligosaccharide-forming Amylase from Pseudomonas saccharophila STB07 | Descriptor: | CALCIUM ION, GLYCEROL, Glucan 1,4-alpha-maltotetraohydrolase | Authors: | Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H. | Deposit date: | 2018-12-05 | Release date: | 2019-12-11 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Structure of maltotetraose-forming amylase from Pseudomonas saccharophila STB07 provides insights into its product specificity. Int.J.Biol.Macromol., 154, 2020
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6JQB
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![BU of 6jqb by Molmil](/molmil-images/mine/6jqb) | The structure of maltooligosaccharide-forming amylase from Pseudomonas saccharophila STB07 with pseudo-maltoheptaose | Descriptor: | 1,2-ETHANEDIOL, ACARBOSE DERIVED HEPTASACCHARIDE, CALCIUM ION, ... | Authors: | Li, Z.F, Ban, X.F, Zhang, Z.Q, Li, C.M, Gu, Z.B, Jin, T.C, Li, Y.L, Shang, Y.H. | Deposit date: | 2019-03-30 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.101 Å) | Cite: | Structure of maltotetraose-forming amylase from Pseudomonas saccharophila STB07 provides insights into its product specificity. Int.J.Biol.Macromol., 154, 2020
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3FXV
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![BU of 3fxv by Molmil](/molmil-images/mine/3fxv) | Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist | Descriptor: | 12-meric peptide from Nuclear receptor coactivator 1, 6-(4-{[3-(3,5-dichloropyridin-4-yl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-2-methylphenyl)-1-methyl-1H-indole-3-carbox ylic acid, NR1H4 protein | Authors: | Feng, S, Yang, M, He, Y, Chen, L, Zhang, Z, Wang, Z, Hong, D, Richter, H, Benson, G.M, Bleicher, K, Grether, U, Martin, R, Plancher, J.-M, Kuhn, B, Rudolph, M.G. | Deposit date: | 2009-01-21 | Release date: | 2009-04-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist Bioorg.Med.Chem.Lett., 19, 2009
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3TN4
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![BU of 3tn4 by Molmil](/molmil-images/mine/3tn4) | Crystal structure of GkaP mutant G209D from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | Deposit date: | 2011-09-01 | Release date: | 2012-09-19 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
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3TN5
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![BU of 3tn5 by Molmil](/molmil-images/mine/3tn5) | Crystal structure of GkaP mutant Y99L from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, PHOSPHATE ION, Phosphotriesterase | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | Deposit date: | 2011-09-01 | Release date: | 2012-09-12 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
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3TN3
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![BU of 3tn3 by Molmil](/molmil-images/mine/3tn3) | Crystal structure of GkaP from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | Deposit date: | 2011-09-01 | Release date: | 2012-09-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
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3TN6
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![BU of 3tn6 by Molmil](/molmil-images/mine/3tn6) | Crystal structure of GkaP mutant R230H from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | Deposit date: | 2011-09-01 | Release date: | 2012-09-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
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3TNB
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![BU of 3tnb by Molmil](/molmil-images/mine/3tnb) | Crystal structure of GkaP mutant G209D/R230H from Geobacillus kaustophilus HTA426 | Descriptor: | COBALT (II) ION, Phosphotriesterase | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | Deposit date: | 2011-09-01 | Release date: | 2012-09-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
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4E55
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![BU of 4e55 by Molmil](/molmil-images/mine/4e55) | |
4E56
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![BU of 4e56 by Molmil](/molmil-images/mine/4e56) | |
8JG8
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![BU of 8jg8 by Molmil](/molmil-images/mine/8jg8) | |
4BH6
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![BU of 4bh6 by Molmil](/molmil-images/mine/4bh6) | Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex | Descriptor: | APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 | Authors: | He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. | Deposit date: | 2013-03-29 | Release date: | 2013-06-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
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3H1K
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![BU of 3h1k by Molmil](/molmil-images/mine/3h1k) | Chicken cytochrome BC1 complex with ZN++ and an iodinated derivative of kresoxim-methyl bound | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | Authors: | Berry, E.A, Zhang, Z, Bellamy, H.D, Huang, L.S. | Deposit date: | 2009-04-12 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Crystallographic location of two Zn(2+)-binding sites in the avian cytochrome bc(1) complex Biochim.Biophys.Acta, 1459, 2000
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7D3Y
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![BU of 7d3y by Molmil](/molmil-images/mine/7d3y) | Crystal structure of the osPHR2-osSPX2 complex | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | Authors: | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | Deposit date: | 2020-09-21 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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6M4Q
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![BU of 6m4q by Molmil](/molmil-images/mine/6m4q) | Cytochrome P450 monooxygenase StvP2 substrate-free structure | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | Deposit date: | 2020-03-08 | Release date: | 2020-08-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
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2ONC
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![BU of 2onc by Molmil](/molmil-images/mine/2onc) | Crystal structure of human DPP-4 | Descriptor: | 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Feng, J, Zhang, Z, Wallace, M.B, Stafford, J.A, Kaldor, S.W, Kassel, D.B, Navre, M, Shi, L, Skene, R.J, Asakawa, T, Takeuchi, K, Xu, R, Webb, D.R, Gwaltney, S.L. | Deposit date: | 2007-01-23 | Release date: | 2008-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV. J.Med.Chem., 50, 2007
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6M4P
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![BU of 6m4p by Molmil](/molmil-images/mine/6m4p) | Cytochrome P450 monooxygenase StvP2 substrate-bound structure | Descriptor: | 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | Deposit date: | 2020-03-08 | Release date: | 2020-08-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
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5SV9
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![BU of 5sv9 by Molmil](/molmil-images/mine/5sv9) | Structure of the SLC4 transporter Bor1p in an inward-facing conformation | Descriptor: | Bor1p boron transporter | Authors: | Coudray, N, Seyler, S, Lasala, R, Zhang, Z, Clark, K.M, Dumont, M.E, Rohou, A, Beckstein, O, Stokes, D.L, Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) | Deposit date: | 2016-08-05 | Release date: | 2016-08-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structure of the SLC4 transporter Bor1p in an inward-facing conformation. Protein Sci., 26, 2017
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