7XH6
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![BU of 7xh6 by Molmil](/molmil-images/mine/7xh6) | Crystal structure of CBP bromodomain liganded with CCS1477 | Descriptor: | (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, DIMETHYL SULFOXIDE, ... | Authors: | Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-04-07 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
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6LG4
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6LG8
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6LG9
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7XHE
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![BU of 7xhe by Molmil](/molmil-images/mine/7xhe) | Crystal structure of CBP bromodomain liganded with CCS151 | Descriptor: | (6S)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]-1-(3-fluoranyl-4-methoxy-phenyl)piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein | Authors: | Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-04-08 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
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7XI0
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![BU of 7xi0 by Molmil](/molmil-images/mine/7xi0) | Crystal structure of CBP bromodomain liganded with CCS150 | Descriptor: | (6S)-1-(3-chloranyl-4-methoxy-phenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, GLYCEROL | Authors: | Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-04-11 | Release date: | 2022-07-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
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4ZWJ
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![BU of 4zwj by Molmil](/molmil-images/mine/4zwj) | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | Descriptor: | Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin | Authors: | Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR) | Deposit date: | 2015-05-19 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.302 Å) | Cite: | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature, 523, 2015
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3CJW
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5VRO
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![BU of 5vro by Molmil](/molmil-images/mine/5vro) | ABA-mimicking ligand AMF1beta in complex with ABA receptor PYL2 and PP2C HAB1 | Descriptor: | 1-(3-fluoro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ... | Authors: | Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K. | Deposit date: | 2017-05-11 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.257 Å) | Cite: | Combining chemical and genetic approaches to increase drought resistance in plants. Nat Commun, 8, 2017
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5VT7
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![BU of 5vt7 by Molmil](/molmil-images/mine/5vt7) | ABA-mimicking ligand AMC1beta in complex with ABA receptor PYL2 and PP2C HAB1 | Descriptor: | 1-(3-chloro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ... | Authors: | Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.X, Zhu, J.-K. | Deposit date: | 2017-05-15 | Release date: | 2017-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.624 Å) | Cite: | Combining chemical and genetic approaches to increase drought resistance in plants. Nat Commun, 8, 2017
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4P6W
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![BU of 4p6w by Molmil](/molmil-images/mine/4p6w) | Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain | Descriptor: | Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2 | Authors: | He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E. | Deposit date: | 2014-03-25 | Release date: | 2014-04-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.951 Å) | Cite: | Structures and mechanism for the design of highly potent glucocorticoids. Cell Res., 24, 2014
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8I2G
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![BU of 8i2g by Molmil](/molmil-images/mine/8i2g) | FSHR-Follicle stimulating hormone-compound 716340-Gs complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | Deposit date: | 2023-01-14 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8IRV
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![BU of 8irv by Molmil](/molmil-images/mine/8irv) | Dopamine Receptor D5R-Gs-Rotigotine complex | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | Deposit date: | 2023-03-19 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
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8I2H
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![BU of 8i2h by Molmil](/molmil-images/mine/8i2h) | Follicle stimulating hormone receptor | Descriptor: | Follicle-stimulating hormone receptor | Authors: | Duan, J, Xu, P, Yang, J, Ji, Y, Zhang, H, Mao, C, Luan, X, Jiang, Y, Zhang, Y, Zhang, S, Xu, H.E. | Deposit date: | 2023-01-14 | Release date: | 2023-03-22 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor. Nat Commun, 14, 2023
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8IBV
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![BU of 8ibv by Molmil](/molmil-images/mine/8ibv) | Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | Jiang, Y, Xu, H.E, You, C, Xu, Y. | Deposit date: | 2023-02-10 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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8IBU
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![BU of 8ibu by Molmil](/molmil-images/mine/8ibu) | Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex | Descriptor: | ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | You, C, Jiang, Y, Xu, H.E, Xu, Y. | Deposit date: | 2023-02-10 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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8IRR
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![BU of 8irr by Molmil](/molmil-images/mine/8irr) | Dopamine Receptor D1R-Gs-Rotigotine complex | Descriptor: | CHOLESTEROL, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | Deposit date: | 2023-03-19 | Release date: | 2023-06-21 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
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8IRU
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![BU of 8iru by Molmil](/molmil-images/mine/8iru) | Dopamine Receptor D4R-Gi-Rotigotine complex | Descriptor: | CHOLESTEROL, D(4) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | Deposit date: | 2023-03-19 | Release date: | 2023-06-21 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
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8IRT
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![BU of 8irt by Molmil](/molmil-images/mine/8irt) | Dopamine Receptor D3R-Gi-Rotigotine complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | Deposit date: | 2023-03-19 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
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8IRS
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![BU of 8irs by Molmil](/molmil-images/mine/8irs) | Dopamine Receptor D2R-Gi-Rotigotine complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. | Deposit date: | 2023-03-19 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
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4PW2
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![BU of 4pw2 by Molmil](/molmil-images/mine/4pw2) | Crystal structure of D-glucuronyl C5 epimerase | Descriptor: | CITRIC ACID, D-glucuronyl C5 epimerase B | Authors: | Ke, J, Qin, Y, Gu, X, Brunzelle, J.S, Xu, H.E, Ding, K. | Deposit date: | 2014-03-18 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Study of d-Glucuronyl C5-epimerase. J.Biol.Chem., 290, 2015
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7CZ5
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![BU of 7cz5 by Molmil](/molmil-images/mine/7cz5) | Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | Descriptor: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-07 | Release date: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for activation of the growth hormone-releasing hormone receptor. Nat Commun, 11, 2020
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8I6U
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![BU of 8i6u by Molmil](/molmil-images/mine/8i6u) | The cryo-EM structure of OsCyc1 dimer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
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8I6T
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![BU of 8i6t by Molmil](/molmil-images/mine/8i6t) | The cryo-EM structure of OsCyc1 hexamer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
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8I6P
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![BU of 8i6p by Molmil](/molmil-images/mine/8i6p) | The cryo-EM structure of OsCyc1 tetramer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
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