8IRR
Dopamine Receptor D1R-Gs-Rotigotine complex
Summary for 8IRR
Entry DOI | 10.2210/pdb8irr/pdb |
EMDB information | 35683 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total) |
Functional Keywords | dopamine, dopamine receptor, gpcr, d1r, gs, rotigotine, parkinson's disease, restless legs syndrome, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 147491.81 |
Authors | |
Primary citation | Xu, P.,Huang, S.,Krumm, B.E.,Zhuang, Y.,Mao, C.,Zhang, Y.,Wang, Y.,Huang, X.P.,Liu, Y.F.,He, X.,Li, H.,Yin, W.,Jiang, Y.,Zhang, Y.,Roth, B.L.,Xu, H.E. Structural genomics of the human dopamine receptor system. Cell Res., 33:604-616, 2023 Cited by PubMed: 37221270DOI: 10.1038/s41422-023-00808-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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