6LG4
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-1024
Summary for 6LG4
Entry DOI | 10.2210/pdb6lg4/pdb |
Descriptor | Bromodomain-containing protein 4, 7-chloranyl-5-nitro-quinolin-8-ol (3 entities in total) |
Functional Keywords | brd4, inhibitor, complex, dna binding protein, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15107.79 |
Authors | |
Primary citation | Xu, H.,Zuo, Y.,Zhang, H. Lead-Opt: An efficient tool for structural optimization of lead compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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