6LG4
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-1024
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 125 | 14883.2 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (A) | 7-chloranyl-5-nitro-quinolin-8-ol | non-polymer | 224.6 | 1 | Chemie (EC0) | |||
| 3 | C (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 44 - 167 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14883.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 224.6 | |
| All* | Total formula weight | 15107.8 |
