3X40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x40 by Molmil](/molmil-images/mine/3x40) | Copper amine oxidase from Arthrobacter globiformis: Product Schiff-base form produced by anaerobic reduction in the presence of sodium chloride | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Okajima, T, Nakanishi, S, Murakawa, T, Kataoka, M, Hayashi, H, Hamaguchi, A, Nakai, T, Kawano, Y, Yamaguchi, H, Tanizawa, K. | 登録日 | 2015-03-10 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions. J.Biol.Chem., 290, 2015
|
|
8IFG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ifg by Molmil](/molmil-images/mine/8ifg) | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | 分子名称: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | 著者 | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | 登録日 | 2023-02-17 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
|
|
2ID0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2id0 by Molmil](/molmil-images/mine/2id0) | Escherichia coli RNase II | 分子名称: | Exoribonuclease 2, MANGANESE (II) ION | 著者 | Zuo, Y, Zhang, J, Wang, Y, Malhotra, A. | 登録日 | 2006-09-13 | 公開日 | 2006-10-03 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for Processivity and Single-Strand Specificity of RNase II. Mol.Cell, 24, 2006
|
|
2IEO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ieo by Molmil](/molmil-images/mine/2ieo) | Crystal structure analysis of HIV-1 protease mutant I84V with a potent non-peptide inhibitor (UIC-94017) | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Protease, ... | 著者 | Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T. | 登録日 | 2006-09-19 | 公開日 | 2006-10-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains. J.Mol.Biol., 338, 2004
|
|
1K1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k1u by Molmil](/molmil-images/mine/1k1u) | Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN | 著者 | Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T. | 登録日 | 2001-09-25 | 公開日 | 2002-07-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Combining mutations in HIV-1 protease to understand mechanisms of resistance. Proteins, 48, 2002
|
|
1K2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k2b by Molmil](/molmil-images/mine/1k2b) | Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN | 著者 | Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T. | 登録日 | 2001-09-26 | 公開日 | 2002-07-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Combining mutations in HIV-1 protease to understand mechanisms of resistance. Proteins, 48, 2002
|
|
6J0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j0b by Molmil](/molmil-images/mine/6j0b) | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath-tube complex in extended state | 分子名称: | Pvc1, Pvc2 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-23 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
|
|
6J0C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j0c by Molmil](/molmil-images/mine/6j0c) | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath complex in contracted state | 分子名称: | Pvc2 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-23 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
|
|
6J0F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j0f by Molmil](/molmil-images/mine/6j0f) | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath/tube terminator in extended state | 分子名称: | Pvc1, Pvc16 | 著者 | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | 登録日 | 2018-12-24 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
|
|
4R0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r0s by Molmil](/molmil-images/mine/4r0s) | Crystal structure of P. aeruginosa TpbA | 分子名称: | GLYCEROL, PHOSPHATE ION, Protein tyrosine phosphatase TpbA | 著者 | Xu, K, Li, S, Wang, Y, Bartlam, M. | 登録日 | 2014-08-01 | 公開日 | 2015-05-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1 PLoS ONE, 10, 2015
|
|
5DGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dgw by Molmil](/molmil-images/mine/5dgw) | Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand | 分子名称: | (3R,3aS,4S,7aS)-3-(ethylamino)hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Pol protein, ... | 著者 | Agniswamy, J, Wang, Y.-F, Weber, I.T. | 登録日 | 2015-08-28 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands. Org.Biomol.Chem., 13, 2015
|
|
6JE9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6je9 by Molmil](/molmil-images/mine/6je9) | Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | 登録日 | 2019-02-04 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
|
|
5H7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h7o by Molmil](/molmil-images/mine/5h7o) | Crystal structure of DJ-101 in complex with tubulin protein | 分子名称: | 2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Arnst, K, Wang, Y, Hwang, D.-J, Xue, Y, Costello, T, Hamilton, D, Chen, Q, Yang, J, Park, F, Dalton, J.T, Miller, D.D, Li, W. | 登録日 | 2016-11-20 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance. Cancer Res., 78, 2018
|
|
3X3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x3y by Molmil](/molmil-images/mine/3x3y) | Copper amine oxidase from Arthrobacter globiformis anaerobically reduced by histamine | 分子名称: | COPPER (II) ION, GLYCEROL, POTASSIUM ION, ... | 著者 | Okajima, T, Nakanishi, S, Murakawa, T, Kataoka, M, Hayashi, H, Hamaguchi, A, Nakai, T, Kawano, Y, Yamaguchi, H, Tanizawa, K. | 登録日 | 2015-03-10 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions. J.Biol.Chem., 290, 2015
|
|
6PDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pdr by Molmil](/molmil-images/mine/6pdr) | |
1JR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jr6 by Molmil](/molmil-images/mine/1jr6) | |
6PDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pdu by Molmil](/molmil-images/mine/6pdu) | Vaccine-elicited NHP FP-targeting antibody 13N024-a.01 in complex with HIV fusion peptide (residue 512-519) | 分子名称: | HIV-1 fusion peptide residue 512-519, antibody 13N024-a.01, heavy chain, ... | 著者 | Xu, K, Liu, K, Wang, Y, Kwong, P.D. | 登録日 | 2019-06-19 | 公開日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | 主引用文献 | Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies To Be Published
|
|
3ZIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zif by Molmil](/molmil-images/mine/3zif) | Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | 分子名称: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | 著者 | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | 登録日 | 2013-01-09 | 公開日 | 2014-01-22 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates Virology, 450, 2014
|
|
5KPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kpp by Molmil](/molmil-images/mine/5kpp) | Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | 1-[[4-fluoranyl-3-[(3R)-3-methyl-4-[2,2,2-tris(fluoranyl)ethyl]piperazin-1-yl]carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1 | 著者 | Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. | 登録日 | 2016-07-05 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
|
|
8IL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8il4 by Molmil](/molmil-images/mine/8il4) | |
5HOT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hot by Molmil](/molmil-images/mine/5hot) | Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase | 分子名称: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase | 著者 | Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D. | 登録日 | 2016-01-19 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
|
|
1T2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t2l by Molmil](/molmil-images/mine/1t2l) | Three Crystal Structures of Human Coactosin-like Protein | 分子名称: | Coactosin-like protein | 著者 | Liu, L, Wei, Z, Chen, Z, Wang, Y, Gong, W. | 登録日 | 2004-04-22 | 公開日 | 2004-11-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Human Coactosin-like Protein J.Mol.Biol., 344, 2004
|
|
1T3X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t3x by Molmil](/molmil-images/mine/1t3x) | |
1T3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t3y by Molmil](/molmil-images/mine/1t3y) | |
1SVS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1svs by Molmil](/molmil-images/mine/1svs) | Structure of the K180P mutant of Gi alpha subunit bound to GppNHp. | 分子名称: | Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, ... | 著者 | Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R. | 登録日 | 2004-03-29 | 公開日 | 2004-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit. Proc.Natl.Acad.Sci.USA, 101, 2004
|
|