1SVS

Structure of the K180P mutant of Gi alpha subunit bound to GppNHp.

Summary for 1SVS

• Entry DOI: 10.2210/pdb1svs/pdb
• Related: 1SVK
• Descriptor: Guanine nucleotide-binding protein G(i), alpha-1 subunit, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
• Functional Keywords: gi alpha subunit, k180p mutation, gppnhp (gnp) bound, hydrolase, signaling protein
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Nucleus: P10824
• Total number of polymer chains: 1
• Total formula weight: 40782.27

Authors

Thomas, C.J.,Du, X.,Li, P.,Wang, Y.,Ross, E.M.,Sprang, S.R. (deposition date: 2004-03-29, release date: 2004-06-01, Last modification date: 2024-02-14)

• Primary citation: Thomas, C.J.,Du, X.,Li, P.,Wang, Y.,Ross, E.M.,Sprang, S.R.; Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit.; Proc.Natl.Acad.Sci.USA, 101:7560-7565, 2004; PubMed: 15128951; DOI: 10.1073/pnas.0304091101

Experimental method

X-RAY DIFFRACTION (1.5 Å)