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PDB: 12895 件

1ONP
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IspC complex with Mn2+ and fosmidomycin
分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, MANGANESE (II) ION
著者Steinbacher, S, Kaiser, J, Eisenreich, W, Huber, R, Bacher, A, Rohdich, F.
登録日2003-02-28
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development.
J.BIOL.CHEM., 278, 2003
5AYE
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Crystal structure of Ruminococcus albus beta-(1,4)-mannooligosaccharide phosphorylase (RaMP2) in complexes with phosphate and beta-(1,4)-mannobiose
分子名称: Beta-1,4-mannooligosaccharide phosphorylase, PHOSPHATE ION, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose
著者Ye, Y, Saburi, W, Kato, K, Yao, M.
登録日2015-08-13
公開日2016-03-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the difference in substrate recognition of two mannoside phosphorylases from two GH130 subfamilies.
Febs Lett., 590, 2016
3VSG
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Crystal structure of iron free 1,6-APD, 2-Animophenol-1,6-Dioxygenase
分子名称: 2-amino-5-chlorophenol 1,6-dioxygenase alpha subunit, 2-amino-5-chlorophenol 1,6-dioxygenase beta subunit
著者Li, D.F, Hou, Y.J, Hu, Y, Wang, D.C, Liu, W.
登録日2012-04-25
公開日2013-01-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of aminophenol dioxygenase in complex with intermediate, product and inhibitor
Acta Crystallogr.,Sect.D, 69, 2013
3EZ2
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Partition protein-ADP complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Schumacher, M.A, Dunham, T.D, Xu, W, Funnell, B.
登録日2008-10-22
公開日2009-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
3F0C
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Crystal structure of transcriptional regulator from Cytophaga hutchinsonii ATCC 33406
分子名称: SULFATE ION, Transcriptional regulator
著者Nocek, B, Maltseva, N, Tan, K, Abdullah, J, Eschenfeldt, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-10-24
公開日2008-11-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Crystal structure of transcriptional regulator from Cytophaga hutchinsonii ATCC 33406
To be Published
3I4A
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Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine
分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N5-(1-iminopropyl)-L-ornithine
著者Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Fast, W, Robertus, J.D.
登録日2009-07-01
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
3I5W
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Crystal structure of human alpha-defensin 5 (mutant R13H)
分子名称: CHLORIDE ION, CITRATE ANION, Defensin-5
著者Pazgier, M, Lu, W.
登録日2009-07-06
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5
Febs Lett., 583, 2009
3VP7
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Crystal structure of the beta-alpha repeated, autophagy-specific (BARA) domain of Vps30/Atg6
分子名称: Vacuolar protein sorting-associated protein 30
著者Noda, N.N, Kobayashi, T, Adachi, W, Fujioka, Y, Ohsumi, Y, Inagaki, F.
登録日2012-02-28
公開日2012-03-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy.
J.Biol.Chem., 287, 2012
7ZCH
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CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
3VPI
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Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa
分子名称: FORMIC ACID, type VI secretion exported 1
著者Ding, J, Wang, W, Wang, D.C.
登録日2012-03-04
公開日2012-06-27
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insights into the Pseudomonas aeruginosa type VI virulence effector Tse1 bacteriolysis and self-protection mechanisms
J.Biol.Chem., 287, 2012
3IZJ
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Mm-cpn rls with ATP and AlFx
分子名称: Chaperonin
著者Douglas, N.R, Reissmann, S, Zhang, J, Chen, B, Jakana, J, Kumar, R, Chiu, W, Frydman, J.
登録日2010-10-29
公開日2011-02-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Dual Action of ATP Hydrolysis Couples Lid Closure to Substrate Release into the Group II Chaperonin Chamber.
Cell(Cambridge,Mass.), 144, 2011
1ORV
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Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
著者Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H.
登録日2003-03-16
公開日2003-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
3J0G
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Homology model of E3 protein of Venezuelan Equine Encephalitis Virus TC-83 strain fitted with a cryo-EM map
分子名称: E3 protein
著者Zhang, R, Hryc, C.F, Chiu, W.
登録日2011-07-21
公開日2011-08-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献4.4 angstrom cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus.
Embo J., 30, 2011
5AY7
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A psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase
分子名称: xylanase
著者Zheng, Y, Li, Y, Liu, W, Guo, R.T.
登録日2015-08-10
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase.
J.Struct.Biol., 193, 2016
7ZCG
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CHMP2A-CHMP3 heterodimer (430 Angstrom diameter)
分子名称: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
著者Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
登録日2022-03-28
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
3F5X
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CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site
分子名称: 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2, Cyclin-A2, ...
著者Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X.
登録日2008-11-04
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
Bioorg.Med.Chem.Lett., 19, 2009
3VW5
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Crystal structure of sugar epimerase from ruminal bacterium
分子名称: Cellobiose 2-epimerase
著者Fujiwara, T, Saburi, W, Tanaka, I, Yao, M.
登録日2012-08-02
公開日2013-06-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Ruminococcus albus cellobiose 2-epimerase: structural insights into epimerization of unmodified sugar
Febs Lett., 587, 2013
2JZ1
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DSX_long
分子名称: Protein doublesex
著者Yang, Y, Zhang, W, Bayrer, J.R, Weiss, M.A.
登録日2007-12-21
公開日2008-01-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster: STRUCTURE, FUNCTION, AND MUTAGENESIS OF A FEMALE-SPECIFIC DOMAIN.
J.Biol.Chem., 283, 2008
1P0N
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IPP:DMAPP isomerase type II, FMN complex
分子名称: FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase
著者Steinbacher, S, Kaiser, J, Gerhardt, S, Eisenreich, W, Huber, R, Bacher, A, Rohdich, F.
登録日2003-04-10
公開日2003-06-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase from Bacillus subtilis
J.Mol.Biol., 329, 2003
1P1D
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Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
分子名称: Glutamate receptor interacting protein
著者Feng, W, Shi, Y, Li, M, Zhang, M.
登録日2003-04-12
公開日2003-11-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
5BP7
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Crystal structure of SAM-dependent methyltransferase from Geobacter sulfurreducens in complex with S-Adenosyl-L-homocysteine
分子名称: CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase
著者Kutner, J, Shabalin, I.G, Mason, D.V, Handing, K.B, Gasiorowska, O.A, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2015-05-27
公開日2015-06-10
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of SAM-dependent methyltransferase from Geobacter sulfurreducens in complex with S-Adenosyl-L-homocysteine
to be published
1P49
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Structure of Human Placental Estrone/DHEA Sulfatase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHATE ION, ...
著者Hernandez-Guzman, F.G, Higashiyama, T, Pangborn, W, Osawa, Y, Ghosh, D.
登録日2003-04-21
公開日2003-08-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association
J.Biol.Chem., 278, 2003
7W1N
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Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KRP
分子名称: 1,2-ETHANEDIOL, BICINE, Leaf-branch compost cutinase
著者Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T.
登録日2021-11-19
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy.
Acs Catalysis, 12, 2022
3VPO
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Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
分子名称: FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2
著者Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J.
登録日2012-03-05
公開日2013-03-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Essential role of E106 in the proton-coupled electron transfer in human
to be published
7W44
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Complex structure of a leaf-branch compost cutinase variant LCC ICCG_RIP
分子名称: 1,2-ETHANEDIOL, IMIDAZOLE, Leaf-branch compost cutinase
著者Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T.
登録日2021-11-26
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy.
Acs Catalysis, 12, 2022

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