3I5W

Crystal structure of human alpha-defensin 5 (mutant R13H)

Summary for 3I5W

• Entry DOI: 10.2210/pdb3i5w/pdb
• Related: 1ZMP 3GNY
• Descriptor: Defensin-5, CITRATE ANION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: human alpha-defensin 5, hd5, antimicrobial peptide, antibiotic, antimicrobial, defensin, disulfide bond, fungicide, secreted, antimicrobial protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: Q01523
• Total number of polymer chains: 2
• Total formula weight: 7374.92

Authors

Pazgier, M.,Lu, W. (deposition date: 2009-07-06, release date: 2009-07-28, Last modification date: 2023-09-06)

• Primary citation: de Leeuw, E.,Rajabi, M.,Zou, G.,Pazgier, M.,Lu, W.; Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5; Febs Lett., 583:2507-2512, 2009; PubMed: 19589339; DOI: 10.1016/j.febslet.2009.06.051

Experimental method

X-RAY DIFFRACTION (1.63 Å)