5HSZ
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4QE9
| Open MthK pore structure soaked in 10 mM Ba2+/100 mM K+ | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S. | Deposit date: | 2014-05-15 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Ionic interactions of Ba2+ blockades in the MthK K+ channel J.Gen.Physiol., 144, 2014
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4ZBM
| Crystal structure of Drosophila cyclic nucleotide gated channel pore mimicking NaK mutant | Descriptor: | BARIUM ION, POTASSIUM ION, Potassium channel protein | Authors: | Lam, Y, Zeng, W, Derebe, M.G, Jiang, Y. | Deposit date: | 2015-04-14 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels. J.Gen.Physiol., 146, 2015
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2AXL
| Solution structure of a multifunctional DNA- and protein-binding domain of human Werner syndrome protein | Descriptor: | Werner syndrome | Authors: | Hu, J.-S, Feng, H, Zeng, W, Lin, G.-X, Xi, X.G. | Deposit date: | 2005-09-05 | Release date: | 2005-12-13 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein. Proc.Natl.Acad.Sci.Usa, 102, 2005
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5E1J
| Structure of voltage-gated two-pore channel TPC1 from Arabidopsis thaliana | Descriptor: | BARIUM ION, CALCIUM ION, Two pore calcium channel protein 1 | Authors: | Guo, J, Zeng, W, Chen, Q, Lee, C, Chen, L, Yang, Y, Jiang, Y. | Deposit date: | 2015-09-29 | Release date: | 2015-12-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.308 Å) | Cite: | Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana. Nature, 531, 2016
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5E1L
| Structural and functional analysis of the E. coli FtsZ interacting protein, ZapC, reveals insight into molecular properties of a novel Z ring stabilizing protein | Descriptor: | Cell division protein ZapC | Authors: | Schumacher, M.A, Huang, K.-H, Tchorzewski, L, Zeng, W, Janakiraman, A. | Deposit date: | 2015-09-29 | Release date: | 2015-12-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and Functional Analyses Reveal Insights into the Molecular Properties of the Escherichia coli Z Ring Stabilizing Protein, ZapC. J.Biol.Chem., 291, 2016
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1L8Z
| Solution structure of HMG box 5 in human upstream binding factor | Descriptor: | upstream binding factor 1 | Authors: | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | Deposit date: | 2002-03-22 | Release date: | 2002-06-05 | Last modified: | 2022-12-21 | Method: | SOLUTION NMR | Cite: | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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1L8Y
| Solution structure of HMG box 5 in human upstream binding factor | Descriptor: | upstream binding factor 1 | Authors: | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | Deposit date: | 2002-03-22 | Release date: | 2002-06-05 | Last modified: | 2022-12-21 | Method: | SOLUTION NMR | Cite: | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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8FYF
| Human TMEM175-LAMP1 transmembrane domain only complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-26 | Release date: | 2023-06-28 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8FY5
| Human TMEM175-LAMP1 full-length complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-25 | Release date: | 2023-06-28 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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7W44
| Complex structure of a leaf-branch compost cutinase variant LCC ICCG_RIP | Descriptor: | 1,2-ETHANEDIOL, IMIDAZOLE, Leaf-branch compost cutinase | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-26 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7W1N
| Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KRP | Descriptor: | 1,2-ETHANEDIOL, BICINE, Leaf-branch compost cutinase | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-19 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7VVE
| Complex structure of a leaf-branch compost cutinase variant in complex with mono(2-hydroxyethyl) terephthalic acid | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 4-(2-hydroxyethyloxycarbonyl)benzoic acid, CALCIUM ION, ... | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7W45
| Complex structure of a leaf-branch compost cutinase variant LCC ICCG_KIP | Descriptor: | CALCIUM ION, Leaf-branch compost cutinase, SODIUM ION | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-26 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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7VVC
| Crystal structure of inactive mutant of leaf-branch compost cutinase variant | Descriptor: | ACETATE ION, ACETIC ACID, CALCIUM ION, ... | Authors: | Niu, D, Zeng, W, Huang, J.W, Chen, C.C, Liu, W.D, Guo, R.T. | Deposit date: | 2021-11-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy. Acs Catalysis, 12, 2022
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5HBU
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7VOA
| Crystal structure of SARS-CoV-2 RBD in complex with aRBD5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpaca nanobody | Authors: | Ma, H, Zeng, W.H, Jin, T.C. | Deposit date: | 2021-10-13 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron. Cell Res., 32, 2022
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4GX2
| GsuK channel bound to NAD | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GX1
| Crystal structure of the GsuK bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GX0
| Crystal structure of the GsuK L97D mutant | Descriptor: | CALCIUM ION, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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4GX5
| GsuK Channel | Descriptor: | CALCIUM ION, POTASSIUM ION, TrkA domain protein, ... | Authors: | Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. | Deposit date: | 2012-09-03 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
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3V5U
| Structure of Sodium/Calcium Exchanger from Methanocaldococcus jannaschii DSM 2661 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, CALCIUM ION, ... | Authors: | Jiang, Y, Liao, J, Li, H, Zeng, W, Sauer, D, Belmares, R. | Deposit date: | 2011-12-16 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger. Science, 335, 2012
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3OUF
| Structure of a K+ selective NaK mutant | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein | Authors: | Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2010-09-14 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OUS
| MthK channel pore T59A mutant | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y. | Deposit date: | 2010-09-15 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites. Proc.Natl.Acad.Sci.USA, 108, 2011
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3R65
| MthK channel pore E92Q mutant | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Shi, N, Zeng, W, Ye, S, Li, Y, Jiang, Y. | Deposit date: | 2011-03-21 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crucial points within the pore as determinants of K+ channel conductance and gating J.Mol.Biol., 411, 2011
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