1P49

Structure of Human Placental Estrone/DHEA Sulfatase

Summary for 1P49

Entry DOI	10.2210/pdb1p49/pdb
Descriptor	STERYL-SULFATASE, octyl beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	steroid biosynthesis, steroid sulfatase, estrone sulfate, dehydroepiandrosterone sulfate, human placental enzyme, endoplasmic reticulum membrane-bound, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein: P08842
Total number of polymer chains	1
Total formula weight	64214.03
Authors	Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D. (deposition date: 2003-04-21, release date: 2003-08-12, Last modification date: 2020-07-29)
Primary citation	Hernandez-Guzman, F.G.,Higashiyama, T.,Pangborn, W.,Osawa, Y.,Ghosh, D. Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association J.Biol.Chem., 278:22989-22997, 2003 Cited by PubMed: 12657638 DOI: 10.1074/jbc.M211497200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation