7ZCH

CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)

Summary for 7ZCH

Entry DOI	10.2210/pdb7zch/pdb
EMDB information	14631
Descriptor	Charged multivesicular body protein 2a, Charged multivesicular body protein 3 (2 entities in total)
Functional Keywords	cryo electron microscopy, helical reconstruction, membrane-bound chmp2a-chmp3 filament, negative-curvature membrane, cytosolic protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	35735.17
Authors	Azad, K.,Desfosses, A.,Effantin, G.,Schoehn, G.,Weissenhorn, W. (deposition date: 2022-03-28, release date: 2023-01-18, Last modification date: 2023-02-01)
Primary citation	Azad, K.,Guilligay, D.,Boscheron, C.,Maity, S.,De Franceschi, N.,Sulbaran, G.,Effantin, G.,Wang, H.,Kleman, J.P.,Bassereau, P.,Schoehn, G.,Roos, W.H.,Desfosses, A.,Weissenhorn, W. Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage. Nat.Struct.Mol.Biol., 30:81-90, 2023 Cited by PubMed: 36604498 DOI: 10.1038/s41594-022-00867-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation