1ORV

Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26)

Summary for 1ORV

Entry DOI	10.2210/pdb1orv/pdb
Descriptor	dipeptidyl peptidase IV, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	serine protease, oxyanion hole, substrate channeling, drug design, diabetes mellitus, hydrolase
Biological source	Sus scrofa (pig)
Total number of polymer chains	4
Total formula weight	345563.39
Authors	Engel, M.,Hoffmann, T.,Wagner, L.,Wermann, M.,Heiser, U.,Kiefersauer, R.,Huber, R.,Bode, W.,Demuth, H.U.,Brandstetter, H. (deposition date: 2003-03-16, release date: 2003-05-06, Last modification date: 2020-07-29)
Primary citation	Engel, M.,Hoffmann, T.,Wagner, L.,Wermann, M.,Heiser, U.,Kiefersauer, R.,Huber, R.,Bode, W.,Demuth, H.U.,Brandstetter, H. The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism Proc.Natl.Acad.Sci.USA, 100:5063-5068, 2003 Cited by PubMed: 12690074 DOI: 10.1073/pnas.0230620100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation