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PDB: 12521 件

8VJS
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Cryo-EM structure of Tulane virus 9-6-17 variant capsid protein VP1 9-14-18 without DTT treatment
分子名称: Capsid protein
著者Sun, C, Jiang, W.
登録日2024-01-07
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献The 2.6 angstrom Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change.
Biomolecules, 14, 2024
8VJR
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Cryo-EM structure of Tulane virus 9-6-17 variant capsid protein VP1 9-14-18, DTT-treated
分子名称: Capsid protein
著者Sun, C, Jiang, W.
登録日2024-01-07
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献The 2.6 angstrom Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change.
Biomolecules, 14, 2024
3J9Z
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Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-27
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
4QP3
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Crystal Structure of ERK2 in complex with (S)-2-((9H-purin-6-yl)amino)-3-phenylpropan-1-ol
分子名称: (2S)-3-phenyl-2-(9H-purin-6-ylamino)propan-1-ol, Mitogen-activated protein kinase 1
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3JAV
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BU of 3jav by Molmil
Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
分子名称: Inositol 1,4,5-trisphosphate receptor type 1
著者Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I.
登録日2015-06-30
公開日2015-10-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Gating machinery of InsP3R channels revealed by electron cryomicroscopy.
Nature, 527, 2015
3JBT
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Atomic structure of the Apaf-1 apoptosome
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ...
著者Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y.
登録日2015-10-15
公開日2015-11-18
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
4Q8F
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Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', ...
著者Gregory, M.T, Yang, W.
登録日2014-04-26
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JS6
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Crystal structure of apo psk41 parM protein
分子名称: Uncharacterized ParM protein
著者Schumacher, M.A, Xu, W, Firth, N.
登録日2009-09-09
公開日2010-01-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation.
J.Biol.Chem., 285, 2010
3K9P
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The crystal structure of E2-25K and ubiquitin complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
登録日2009-10-16
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
8WWO
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Crystal structure of the AFSV topoisomerase ATPase domain in complex with AMPPNP
分子名称: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Kuang, W, Deng, Z.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-function analysis of the ATPase domain of African swine fever virus topoisomerase.
Mbio, 15, 2024
4QGL
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Acireductone dioxygenase from Bacillus anthracis with three cadmium ions
分子名称: Acireductone dioxygenase, CADMIUM ION
著者Milaczewska, A.M, Chruszcz, M, Majorek, K.A, Porebski, P.J, Borowski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-05-23
公開日2014-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Acireductone dioxygenase from Bacillus anthracis with three cadmium ions
To be Published
3J7A
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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
分子名称: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
著者Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
登録日2014-06-03
公開日2014-07-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
4QP4
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BU of 4qp4 by Molmil
Crystal Structure of ERK2 in complex with N-cyclohexyl-9H-purin-6-amine
分子名称: Mitogen-activated protein kinase 1, N-cyclohexyl-9H-purin-6-amine
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
4QPA
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BU of 4qpa by Molmil
Crystal Structure of ERK2 in complex with 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine
分子名称: 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1
著者Yin, J, Wang, W.
登録日2014-06-22
公開日2015-09-23
最終更新日2015-12-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3JVJ
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BU of 3jvj by Molmil
Crystal structure of the bromodomain 1 in mouse Brd4
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
8VJC
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Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
3JBQ
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Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
分子名称: GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ...
著者Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A.
登録日2015-09-17
公開日2015-09-30
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
J.Biol.Chem., 290, 2015
3JXR
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X-Ray structure of r[CGCG(5-fluoro)CG]2
分子名称: r[CGCG(5-fluoro)CG]2
著者Adamiak, D.A, Milecki, J, Adamiak, R.W, Rypniewski, W.
登録日2009-09-21
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The hydration and unusual hydrogen bonding in the crystal structure of an RNA duplex containing alternating CG base pairs
New J.Chem., 34, 2010
3JZ1
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Crystal structure of human thrombin mutant N143P in E:Na+ form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NITRATE ION, ...
著者Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
登録日2009-09-22
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
4QC2
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Crystal structure of lipopolysaccharide transport protein LptB in complex with ATP and Magnesium ions
分子名称: ABC transporter related protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Wang, Z, Xiang, Q, Zhu, X, Dong, H, He, C, Wang, H, Zhang, Y, Wang, W, Dong, C.
登録日2014-05-09
公開日2014-10-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural and functional studies of conserved nucleotide-binding protein LptB in lipopolysaccharide transport.
Biochem.Biophys.Res.Commun., 452, 2014
8X19
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Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8VJB
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Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8VSI
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Mechanistic Insights Revealed by YbtPQ in the Occluded State
分子名称: ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ...
著者Hu, W, Parkinson, C, Zheng, H.
登録日2024-01-24
公開日2024-04-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanistic Insights Revealed by YbtPQ in the Occluded State.
Biomolecules, 14, 2024
4QEI
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Two distinct conformational states of GlyRS captured in crystal lattice
分子名称: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, tRNA-Gly-CCC-2-2
著者Xie, W, Qin, X, Deng, X, Zhang, Q, Li, Q.
登録日2014-05-16
公開日2015-05-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.875 Å)
主引用文献Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
J.Biol.Chem., 291, 2016
3JZ2
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Crystal structure of human thrombin mutant N143P in E* form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Thrombin heavy chain, ...
著者Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
登録日2009-09-22
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009

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