1P3H
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![BU of 1p3h by Molmil](/molmil-images/mine/1p3h) | Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 10 kDa chaperonin, CALCIUM ION | Authors: | Roberts, M.M, Coker, A.R, Fossati, G, Mascagni, P, Coates, A.R.M, Wood, S.P, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-04-17 | Release date: | 2003-07-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops J.BACTERIOL., 185, 2003
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4WR8
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![BU of 4wr8 by Molmil](/molmil-images/mine/4wr8) | Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) | Descriptor: | 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... | Authors: | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | Deposit date: | 2014-10-23 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
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7UL5
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![BU of 7ul5 by Molmil](/molmil-images/mine/7ul5) | |
7UL3
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![BU of 7ul3 by Molmil](/molmil-images/mine/7ul3) | CryoEM Structure of Inactive H2R Bound to Famotidine, Nb6M, and NabFab | Descriptor: | Histamine H2 receptor, NabFab HC, NabFab LC, ... | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
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7UL2
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![BU of 7ul2 by Molmil](/molmil-images/mine/7ul2) | CryoEM Structure of Inactive NTSR1 Bound to SR48692 and Nb6 | Descriptor: | 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Nanobody 6, Neurotensin receptor 1, ... | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
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7UL4
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![BU of 7ul4 by Molmil](/molmil-images/mine/7ul4) | CryoEM Structure of Inactive MOR Bound to Alvimopan and Mb6 | Descriptor: | Megabody 6, Mu-type opioid receptor, N-[(2S)-2-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl}-3-phenylpropanoyl]glycine | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
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5J7Q
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![BU of 5j7q by Molmil](/molmil-images/mine/5j7q) | Macrophage Migration Inhibitory Factor bound to Inhibitor K664 Derivative | Descriptor: | 4-(imidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Robertson, M.J, Jorgensen, W.L. | Deposit date: | 2016-04-06 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg.Med.Chem.Lett., 26, 2016
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4WRB
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![BU of 4wrb by Molmil](/molmil-images/mine/4wrb) | Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-190) | Descriptor: | 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | Deposit date: | 2014-10-23 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
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5J7P
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5HVT
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![BU of 5hvt by Molmil](/molmil-images/mine/5hvt) | Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2) | Descriptor: | 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Robertson, M.J, Jorgensen, W.L. | Deposit date: | 2016-01-28 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
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5HVS
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![BU of 5hvs by Molmil](/molmil-images/mine/5hvs) | Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305) | Descriptor: | 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... | Authors: | Robertson, M.J, Jorgensen, W.L. | Deposit date: | 2016-01-28 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
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6CBG
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![BU of 6cbg by Molmil](/molmil-images/mine/6cbg) | Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (5) | Descriptor: | 3-(1H-pyrazol-4-yl)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... | Authors: | Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. | Deposit date: | 2018-02-02 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
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6CBH
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![BU of 6cbh by Molmil](/molmil-images/mine/6cbh) | Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (8m) | Descriptor: | 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Robertson, M.J, Krimmer, S.G, Jorgensen, W.L. | Deposit date: | 2018-02-02 | Release date: | 2018-04-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
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7T10
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![BU of 7t10 by Molmil](/molmil-images/mine/7t10) | |
7T11
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![BU of 7t11 by Molmil](/molmil-images/mine/7t11) | |
6CBF
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![BU of 6cbf by Molmil](/molmil-images/mine/6cbf) | |
1XJR
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![BU of 1xjr by Molmil](/molmil-images/mine/1xjr) | The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome | Descriptor: | MAGNESIUM ION, s2m RNA | Authors: | Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G. | Deposit date: | 2004-09-24 | Release date: | 2005-02-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of a rigorously conserved RNA element within the SARS virus genome Plos Biol., 3, 2005
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2OIU
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![BU of 2oiu by Molmil](/molmil-images/mine/2oiu) | L1 Ribozyme Ligase circular adduct | Descriptor: | L1 Ribozyme RNA Ligase, MAGNESIUM ION | Authors: | Robertson, M.P, Scott, W.G. | Deposit date: | 2007-01-11 | Release date: | 2007-03-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structural basis of ribozyme-catalyzed RNA assembly. Science, 315, 2007
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1LR2
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![BU of 1lr2 by Molmil](/molmil-images/mine/1lr2) | Crystal structure of thaumatin at high hydrostatic pressure | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Charron, C, Kadri, A, Robert, M.C, Capelle, B, Giege, R, Lorber, B. | Deposit date: | 2002-05-14 | Release date: | 2003-02-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray diffraction properties of protein crystals
prepared in agarose gel under hydrostatic pressure. J.CRYST.GROWTH, 245, 2002
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1LR3
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![BU of 1lr3 by Molmil](/molmil-images/mine/1lr3) | Crystal structure of thaumatin at high hydrostatic pressure | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Charron, C, Kadri, A, Robert, M.C, Capelle, B, Giege, R, Lorber, B. | Deposit date: | 2002-05-14 | Release date: | 2003-02-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray diffraction properties of protein crystals
prepared in agarose gel under hydrostatic pressure. J.CRYST.GROWTH, 245, 2002
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1U1U
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![BU of 1u1u by Molmil](/molmil-images/mine/1u1u) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-16 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1U1H
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![BU of 1u1h by Molmil](/molmil-images/mine/1u1h) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, SULFATE ION, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-15 | Release date: | 2004-09-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1U22
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![BU of 1u22 by Molmil](/molmil-images/mine/1u22) | A. thaliana cobalamine independent methionine synthase | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-16 | Release date: | 2004-09-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1U1J
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![BU of 1u1j by Molmil](/molmil-images/mine/1u1j) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-15 | Release date: | 2004-09-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1LY0
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![BU of 1ly0 by Molmil](/molmil-images/mine/1ly0) | Structure of thaumatin crystallized in the presence of glycerol | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Charron, C, Kadri, A, Robert, M.C, Giege, R, Lorber, B. | Deposit date: | 2002-06-06 | Release date: | 2003-01-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Crystallization in the presence of glycerol displaces water molecules in the structure of thaumatin. Acta Crystallogr.,Sect.D, 58, 2002
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