6CBG
Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (5)
Summary for 6CBG
| Entry DOI | 10.2210/pdb6cbg/pdb |
| Descriptor | Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | inhibitor, complex, cytokine |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 38846.76 |
| Authors | Robertson, M.J.,Krimmer, S.G.,Jorgensen, W.L. (deposition date: 2018-02-02, release date: 2018-04-04, Last modification date: 2023-10-04) |
| Primary citation | Trivedi-Parmar, V.,Robertson, M.J.,Cisneros, J.A.,Krimmer, S.G.,Jorgensen, W.L. Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13:1092-1097, 2018 Cited by PubMed: 29575754DOI: 10.1002/cmdc.201800158 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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