7CV4
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![BU of 7cv4 by Molmil](/molmil-images/mine/7cv4) | Quadruplex-duplex hybrid structure in the PIM1 gene, Form 2 | Descriptor: | DNA (26-MER) | Authors: | Winnerdy, F.R, Tan, D.T.J, Lim, K.W, Phan, A.T. | Deposit date: | 2020-08-25 | Release date: | 2020-10-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Coexistence of two quadruplex-duplex hybrids in the PIM1 gene. Nucleic Acids Res., 48, 2020
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7VF1
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![BU of 7vf1 by Molmil](/molmil-images/mine/7vf1) | |
2GKU
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![BU of 2gku by Molmil](/molmil-images/mine/2gku) | Monomeric human telomere DNA tetraplex with 3+1 strand fold topology, two edgewise loops and double-chain reversal loop, NMR, 12 structures | Descriptor: | Human telomere DNA | Authors: | Luu, K.N, Phan, A.T, Kuryavyi, V.V, Lacroix, L, Patel, D.J. | Deposit date: | 2006-04-03 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in k(+) solution: an intramolecular (3 + 1) g-quadruplex scaffold. J.Am.Chem.Soc., 128, 2006
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6AC7
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![BU of 6ac7 by Molmil](/molmil-images/mine/6ac7) | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | Descriptor: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | Authors: | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | Deposit date: | 2018-07-25 | Release date: | 2019-02-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Res., 47, 2019
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6JCE
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![BU of 6jce by Molmil](/molmil-images/mine/6jce) | NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes | Descriptor: | 29-mer DNA | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T. | Deposit date: | 2019-01-28 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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6JCD
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![BU of 6jcd by Molmil](/molmil-images/mine/6jcd) | |
6K3Y
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![BU of 6k3y by Molmil](/molmil-images/mine/6k3y) | G-quadruplex complex with cyclic dinucleotide 3'-3' cGAMP | Descriptor: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, DNA (5'-D(*TP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | Authors: | Winnerdy, F.R, Heddi, B, Phan, A.T. | Deposit date: | 2019-05-22 | Release date: | 2020-01-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides. J.Am.Chem.Soc., 141, 2019
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6K3X
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![BU of 6k3x by Molmil](/molmil-images/mine/6k3x) | |
6KVB
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![BU of 6kvb by Molmil](/molmil-images/mine/6kvb) | Structure of an intra-locked G-quadruplex | Descriptor: | DNA (28-mer) | Authors: | Maity, A, Winnerdy, F.R, Chang, W.D, Chen, G, Phan, A.T. | Deposit date: | 2019-09-03 | Release date: | 2020-03-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs. Nucleic Acids Res., 48, 2020
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6L92
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![BU of 6l92 by Molmil](/molmil-images/mine/6l92) | A basket type G-quadruplex in WNT DNA promoter | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3') | Authors: | Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C. | Deposit date: | 2019-11-08 | Release date: | 2019-12-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. Nucleic Acids Res., 48, 2020
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6L8M
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![BU of 6l8m by Molmil](/molmil-images/mine/6l8m) | WNT DNA promoter mutant G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3') | Authors: | Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C. | Deposit date: | 2019-11-06 | Release date: | 2019-12-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. Nucleic Acids Res., 48, 2020
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1YKQ
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![BU of 1ykq by Molmil](/molmil-images/mine/1ykq) | Crystal structure of Diels-Alder ribozyme | Descriptor: | CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-18 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YKV
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![BU of 1ykv by Molmil](/molmil-images/mine/1ykv) | Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | Descriptor: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-18 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YLS
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![BU of 1yls by Molmil](/molmil-images/mine/1yls) | Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | Descriptor: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-19 | Release date: | 2005-02-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YTY
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![BU of 1yty by Molmil](/molmil-images/mine/1yty) | Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen | Descriptor: | 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein | Authors: | Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. | Deposit date: | 2005-02-11 | Release date: | 2006-01-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
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1ZH5
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![BU of 1zh5 by Molmil](/molmil-images/mine/1zh5) | Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen | Descriptor: | 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein, SULFATE ION | Authors: | Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. | Deposit date: | 2005-04-22 | Release date: | 2006-01-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
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2AQY
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![BU of 2aqy by Molmil](/molmil-images/mine/2aqy) | |
6FQ2
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![BU of 6fq2 by Molmil](/molmil-images/mine/6fq2) | Structure of minimal sequence for left -handed G-quadruplex formation | Descriptor: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | Deposit date: | 2018-02-13 | Release date: | 2018-12-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl., 58, 2019
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2KZD
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![BU of 2kzd by Molmil](/molmil-images/mine/2kzd) | Structure of a (3+1) G-quadruplex formed by hTERT promoter sequence | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*IP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*AP*GP*GP*GP*C)-3') | Authors: | Lim, K.W, Lacroix, L, Yue, D.J.E, Lim, J.K.C, Lim, J.M.W, Phan, A.T. | Deposit date: | 2010-06-16 | Release date: | 2010-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Coexistence of two distinct G-quadruplex conformations in the hTERT promoter J.Am.Chem.Soc., 132, 2010
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2KZE
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![BU of 2kze by Molmil](/molmil-images/mine/2kze) | Structure of an all-parallel-stranded G-quadruplex formed by hTERT promoter sequence | Descriptor: | DNA (5'-D(*AP*IP*GP*GP*GP*AP*GP*GP*GP*IP*CP*TP*GP*GP*GP*AP*GP*GP*GP*C)-3') | Authors: | Lim, K.W, Lacroix, L, Yue, D.J.E, Lim, J.K.C, Lim, J.M.W, Phan, A.T. | Deposit date: | 2010-06-16 | Release date: | 2010-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Coexistence of two distinct G-quadruplex conformations in the hTERT promoter J.Am.Chem.Soc., 132, 2010
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2MB2
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![BU of 2mb2 by Molmil](/molmil-images/mine/2mb2) | parallel-stranded G-quadruplex in DNA poly-G stretches | Descriptor: | DNA_(5'-D(*TP*TP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*T)-3') | Authors: | Sengar, A, Heddi, B, Phan, A.T. | Deposit date: | 2013-07-24 | Release date: | 2014-12-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Formation of g-quadruplexes in poly-g sequences: structure of a propeller-type parallel-stranded g-quadruplex formed by a g15 stretch. Biochemistry, 53, 2014
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2M91
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![BU of 2m91 by Molmil](/molmil-images/mine/2m91) | |
2M90
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![BU of 2m90 by Molmil](/molmil-images/mine/2m90) | |
2MB3
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![BU of 2mb3 by Molmil](/molmil-images/mine/2mb3) | Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative | Descriptor: | (12S,27S)-12,27-bis(4-aminobutyl)-4,30-dimethyl-3,7,14,18,22,29-hexaoxa-11,26,31,32,33,34,35,36-octaazaheptacyclo[26.2. 1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]hexatriaconta-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-dode caene-10,25-dione, DNA_(5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3') | Authors: | Chung, W.J, Heddi, B, Tera, M, Iida, K, Nagasawa, K, Phan, A.T. | Deposit date: | 2013-07-24 | Release date: | 2013-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of an intramolecular (3 + 1) human telomeric g-quadruplex bound to a telomestatin derivative. J.Am.Chem.Soc., 135, 2013
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2MB4
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![BU of 2mb4 by Molmil](/molmil-images/mine/2mb4) | Solution structure of a stacked dimeric G-quadruplex formed by a segment of the human CEB1 minisatellite | Descriptor: | DNA_(5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*TP*GP*G)-3') | Authors: | Adrian, M, Ang, D.J, Lech, C, Heddi, B, Nicolas, A, Phan, A.T. | Deposit date: | 2013-07-25 | Release date: | 2014-05-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Conformational Dynamics of a Stacked Dimeric G-Quadruplex Formed by the Human CEB1 Minisatellite. J.Am.Chem.Soc., 136, 2014
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