6L8M

WNT DNA promoter mutant G-quadruplex

Summary for 6L8M

• Entry DOI: 10.2210/pdb6l8m/pdb
• Descriptor: DNA (5'-D(*GP*GP*GP*TP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3') (1 entity in total)
• Functional Keywords: g-quadruplex, dna promoter, wnt, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 6915.43

Authors

Wang, Z.F.,Li, M.H.,Chu, I.T.,Winnerdy, F.R.,Phan, A.T.,Chang, T.C. (deposition date: 2019-11-06, release date: 2019-12-11, Last modification date: 2023-06-14)

• Primary citation: Wang, Z.F.,Li, M.H.,Chu, I.T.,Winnerdy, F.R.,Phan, A.T.,Chang, T.C.; Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.; Nucleic Acids Res., 48:1120-1130, 2020; PubMed: 31912153; DOI: 10.1093/nar/gkz1207

Experimental method

SOLUTION NMR