6K3Y

G-quadruplex complex with cyclic dinucleotide 3'-3' cGAMP

Summary for 6K3Y

• Entry DOI: 10.2210/pdb6k3y/pdb
• Descriptor: DNA (5'-D(*TP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3'), 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one (2 entities in total)
• Functional Keywords: g-quadruplex, cgamp, dinucleotide, vacancy, dna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 6075.87

Authors

Winnerdy, F.R.,Heddi, B.,Phan, A.T. (deposition date: 2019-05-22, release date: 2020-01-15, Last modification date: 2024-05-15)

• Primary citation: Winnerdy, F.R.,Das, P.,Heddi, B.,Phan, A.T.; Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides.; J.Am.Chem.Soc., 141:18038-18047, 2019; PubMed: 31661272; DOI: 10.1021/jacs.9b05642

Experimental method

SOLUTION NMR