Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 139 件
2QFO
DownloadVisualize
BU of 2qfo by Molmil
HSP90 complexed with A143571 and A516383
分子名称: (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one, 4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE, Heat shock protein HSP 90-alpha
著者Park, C.H.
登録日2007-06-27
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
CHEM.BIOL.DRUG DES., 70, 2007
2QF6
DownloadVisualize
BU of 2qf6 by Molmil
HSP90 complexed with A56322
分子名称: 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE, Heat shock protein HSP 90-alpha
著者Park, C.H.
登録日2007-06-26
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
Chem.Biol.Drug Des., 70, 2007
5UVW
DownloadVisualize
BU of 5uvw by Molmil
BRD4_Bromodomain1-A1376855
分子名称: Bromodomain-containing protein 4, N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide, SULFATE ION
著者Park, C.H.
登録日2017-02-20
公開日2017-06-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献BRD4_Bromodomain1-A1376855
To Be Published
2YWP
DownloadVisualize
BU of 2ywp by Molmil
Crystal Structure of CHK1 with a Urea Inhibitor
分子名称: 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA, Serine/threonine-protein kinase Chk1
著者Park, C.
登録日2007-04-21
公開日2007-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
7VGX
DownloadVisualize
BU of 7vgx by Molmil
Neuropeptide Y Y1 Receptor (NPY1R) in Complex with G Protein and its endogeneous Peptide-Agonist Neuropeptide Y (NPY)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Park, C, Kim, J, Jeong, H, Kang, H, Bang, I, Choi, H.-J.
登録日2021-09-19
公開日2022-02-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of neuropeptide Y signaling through Y1 receptor
Nat Commun, 13, 2022
2EA2
DownloadVisualize
BU of 2ea2 by Molmil
h-MetAP2 complexed with A773812
分子名称: 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Bioorg.Med.Chem.Lett., 17, 2007
2EA4
DownloadVisualize
BU of 2ea4 by Molmil
h-MetAP2 complexed with A797859
分子名称: 2-(2-AMINOETHOXY)-3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Bioorg.Med.Chem.Lett., 17, 2007
5UEO
DownloadVisualize
BU of 5ueo by Molmil
BRD4_BD2_A-1395017
分子名称: Bromodomain-containing protein 4, N-[4-(2,4-difluorophenoxy)-3-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)phenyl]ethanesulfonamide
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Complex structure of BRD4_BD2_A-1395017
To Be Published
5UVX
DownloadVisualize
BU of 5uvx by Molmil
BRD4 Bromodomain 2 with A-1359643
分子名称: Bromodomain-containing protein 4, N-[3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-phenoxyphenyl]methanesulfonamide
著者Park, C.H.
登録日2017-02-20
公開日2017-06-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献BRD4 Bromodomain 2 with A-1359643
To Be Published
2E9N
DownloadVisualize
BU of 2e9n by Molmil
Structure of h-CHK1 complexed with A767085
分子名称: 3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE, Serine/threonine-protein kinase Chk1
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Bioorg.Med.Chem., 15, 2007
2E9O
DownloadVisualize
BU of 2e9o by Molmil
Structure of h-CHK1 complexed with AA582939
分子名称: 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID, Serine/threonine-protein kinase Chk1
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Bioorg.Med.Chem., 15, 2007
2RD6
DownloadVisualize
BU of 2rd6 by Molmil
PARP complexed with A861695
分子名称: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1
著者Park, C.H.
登録日2007-09-21
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献PARP complexed with A861695
To be Published
1PRO
DownloadVisualize
BU of 1pro by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881
分子名称: (5R,6R)-2,4-BIS-(4-HYDROXY-3-METHOXYBENZYL)-1,5-DIBENZYL-3-OXO-6-HYDROXY-1,2,4-TRIAZACYCLOHEPTANE, HIV-1 PROTEASE
著者Park, C.H, Kong, X.P, Dealwis, C.G.
登録日1995-07-18
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
J.Med.Chem., 39, 1996
2GHG
DownloadVisualize
BU of 2ghg by Molmil
h-CHK1 complexed with A431994
分子名称: 5-{5-[(S)-2-AMINO-3-(1H-INDOL-3-YL)-PROPOXYL]-PYRIDIN-3-YL}-3-[1-(1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Serine/threonine-protein kinase Chk1
著者Park, C.
登録日2006-03-27
公開日2007-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancers.
Bioorg.Med.Chem.Lett., 16, 2006
2GA2
DownloadVisualize
BU of 2ga2 by Molmil
h-MetAP2 complexed with A193400
分子名称: 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.
登録日2006-03-07
公開日2007-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties.
Bioorg.Med.Chem.Lett., 16, 2006
2RCW
DownloadVisualize
BU of 2rcw by Molmil
PARP complexed with A620223
分子名称: Poly [ADP-ribose] polymerase 1, trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium
著者Park, C.H.
登録日2007-09-20
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献PARP complexed with A620223
To be Published
1M82
DownloadVisualize
BU of 1m82 by Molmil
SOLUTION STRUCTURE OF THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
分子名称: RNA (25-MER): THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
著者Park, C.-J, Bae, S.-H, Lee, M.-K, Varani, G, Choi, B.-S.
登録日2002-07-24
公開日2003-06-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase
NUCLEIC ACIDS RES., 31, 2003
5UER
DownloadVisualize
BU of 5uer by Molmil
BRD4_BD2_A-1359930
分子名称: Bromodomain-containing protein 4, N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)-4-phenoxyphenyl]methanesulfonamide
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Complex structure of BRD4_BD2_A-1359930
To Be Published
5UEQ
DownloadVisualize
BU of 5ueq by Molmil
BRD4_BD2_A-1390146
分子名称: Bromodomain-containing protein 4, N-[3-(7-methyl-1-oxo-2,6-dihydro-1H-pyrrolo[3,4-d]pyridazin-5-yl)-4-phenoxyphenyl]ethanesulfonamide
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Complex structure of BRD4_BD2_A-1390146
To Be Published
5UEP
DownloadVisualize
BU of 5uep by Molmil
BRD4_BD2_A-581577
分子名称: Bromodomain-containing protein 4, ethyl 3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylate
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Complex structure of BRD4_BD2_A-581577
To Be Published
5UET
DownloadVisualize
BU of 5uet by Molmil
BRD4_BD2_A-1308586
分子名称: 2-methyl-5-phenyl-1H-pyrrole-3-carboxamide, Bromodomain-containing protein 4
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Complex structure of BRD4_BD2_A-1308586
To Be Published
5UEV
DownloadVisualize
BU of 5uev by Molmil
BRD4_BD2_A-556343
分子名称: 1-[5-(2-aminophenyl)-2-methyl-1H-pyrrol-3-yl]ethan-1-one, Bromodomain-containing protein 4
著者Park, C.H.
登録日2017-01-03
公開日2017-06-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Complex structure of BRD4_BD2_A-556343
To Be Published
5UES
DownloadVisualize
BU of 5ues by Molmil
BRD4_BD2_A-1344772
分子名称: 5-[2-(4-chlorophenoxy)phenyl]-2-methyl-1H-pyrrole-3-carboxamide, Bromodomain-containing protein 4
著者Park, C.H.
登録日2017-01-03
公開日2017-06-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Complex structure of BRD4_BD2_A-1344772
To Be Published
5UVT
DownloadVisualize
BU of 5uvt by Molmil
BRD4_BD2_A-1454056
分子名称: 7-(cyclopropylmethyl)-2-methyl-10-[(propan-2-yl)sulfonyl]-2,4,6,7-tetrahydro-3H-2,4,7-triazadibenzo[cd,f]azulen-3-one, Bromodomain-containing protein 4
著者Park, C.H.
登録日2017-02-20
公開日2017-06-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Complex structure of BRD4_BD2_A-1454056
To Be Published
5UVV
DownloadVisualize
BU of 5uvv by Molmil
BRD4 Bromodomain 2 with A-1457066
分子名称: 7-(cyclopropylmethyl)-10-(ethylsulfonyl)-2-methyl-2,4,6,7-tetrahydro-3H-2,4,7-triazadibenzo[cd,f]azulen-3-one, Bromodomain-containing protein 4
著者Park, C.H.
登録日2017-02-20
公開日2017-06-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献BRD4 Bromodomain 2 with A-1457066
To Be Published

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon