2GA2

h-MetAP2 complexed with A193400

Summary for 2GA2

Entry DOI	10.2210/pdb2ga2/pdb
Descriptor	Methionine aminopeptidase 2, MANGANESE (II) ION, 5-BROMO-2-{[(4-CHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, ... (4 entities in total)
Functional Keywords	complex, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	41870.52
Authors	Park, C. (deposition date: 2006-03-07, release date: 2007-03-13, Last modification date: 2011-07-13)
Primary citation	Kawai, M.,BaMaung, N.Y.,Fidanze, S.D.,Erickson, S.A.,Tedrow, J.S.,Sanders, W.J.,Vasudevan, A.,Park, C.,Hutchins, C.,Comess, K.M.,Kalvin, D.,Wang, J.,Zhang, Q.,Lou, P.,Tucker-Garcia, L.,Bouska, J.,Bell, R.L.,Lesniewski, R.,Henkin, J.,Sheppard, G.S. Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties. Bioorg.Med.Chem.Lett., 16:3574-3577, 2006 Cited by PubMed: 16632353 DOI: 10.1016/j.bmcl.2006.03.085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation