8GBE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gbe by Molmil](/molmil-images/mine/8gbe) | |
8GBD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gbd by Molmil](/molmil-images/mine/8gbd) | Homo sapiens Zalpha mutant - P193A | 分子名称: | Double-stranded RNA-specific adenosine deaminase | 著者 | Langeberg, C.J, Vogeli, B, Nichols, P.J, Henen, M, Vicens, Q. | 登録日 | 2023-02-25 | 公開日 | 2023-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome. J.Mol.Biol., 435, 2023
|
|
8GBC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gbc by Molmil](/molmil-images/mine/8gbc) | Homo sapiens Zalpha mutant - N173S | 分子名称: | Double-stranded RNA-specific adenosine deaminase | 著者 | Langeberg, C.J, Nichols, P.J, Henen, M, Vicens, Q, Vogeli, B. | 登録日 | 2023-02-25 | 公開日 | 2023-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome. J.Mol.Biol., 435, 2023
|
|
7SFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sfq by Molmil](/molmil-images/mine/7sfq) | EmrE S64V Mutant Bound to tetra(4-fluorophenyl)phosphonium at pH 8.0 | 分子名称: | Multidrug transporter EmrE, tetrakis(4-fluorophenyl)phosphanium | 著者 | Shcherbakov, A.A, Spreacker, P.J, Dregni, A.J, Henzler-Wildman, K.A, Hong, M. | 登録日 | 2021-10-04 | 公開日 | 2022-03-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | High-pH structure of EmrE reveals the mechanism of proton-coupled substrate transport. Nat Commun, 13, 2022
|
|
5MEN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5men by Molmil](/molmil-images/mine/5men) | Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. | 登録日 | 2016-11-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
|
|
5MHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mha by Molmil](/molmil-images/mine/5mha) | D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with a mixture of 2-ketohexanoic acid and 2-hydroxyhexanoic acid, and NADPH (1.57 A resolution) | 分子名称: | (2R)-2-hydroxyhexanoic acid, 1,2-ETHANEDIOL, 2-Ketohexanoic acid, ... | 著者 | Bisson, C, Baker, P.J, Domenech Perez, J, Pramanpol, N, Harding, S.E, Rice, D.W, Ferrer, J. | 登録日 | 2016-11-23 | 公開日 | 2018-05-09 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism To Be Published
|
|
6O8U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o8u by Molmil](/molmil-images/mine/6o8u) | Crystal structure of IRAK4 in complex with compound 23 | 分子名称: | GLYCEROL, Interleukin-1 receptor-associated kinase 4, N-[2,2-dimethyl-6-(morpholin-4-yl)-2,3-dihydro-1-benzofuran-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, ... | 著者 | Kiefer, J.R, Yu, C, Drobnick, J, Bryan, M.C, Lupardus, P.J. | 登録日 | 2019-03-12 | 公開日 | 2019-05-22 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. J.Med.Chem., 62, 2019
|
|
5DEN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5den by Molmil](/molmil-images/mine/5den) | |
6ORP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6orp by Molmil](/molmil-images/mine/6orp) | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-04-30 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
|
|
5NME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nme by Molmil](/molmil-images/mine/5nme) | 868 TCR in complex with HLA A02 presenting SLYNTVATL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2017-04-05 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
|
|
8GJY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gjy by Molmil](/molmil-images/mine/8gjy) | Structure of a cGAS-like receptor Sp-cGLR1 from S. pistillata | 分子名称: | cGAS-like receptor 1 | 著者 | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
8GJW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gjw by Molmil](/molmil-images/mine/8gjw) | Structure of a cGAS-like receptor Cv-cGLR1 from C. virginica | 分子名称: | SULFATE ION, cGAS-like receptor 1 | 著者 | Li, Y, Morehouse, B.R, Slavik, K.M, Liu, J, Toyoda, H, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
8GJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gjx by Molmil](/molmil-images/mine/8gjx) | Structure of the human STING receptor bound to 2'3'-cUA | 分子名称: | 2'3'-cUA, Stimulator of interferon genes protein | 著者 | Morehouse, B.R, Li, Y, Slavik, K.M, Toyoda, H, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
7C1J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c1j by Molmil](/molmil-images/mine/7c1j) | Crystal structure of the receiver domain of sensor histidine kinase PA1611 (PA1611REC) from Pseudomonas aeruginosa PAO1 with magnesium ion coordinated in the active site cleft | 分子名称: | Histidine kinase, MAGNESIUM ION | 著者 | Chen, S.K, Guan, H.H, Wu, P.H, Lin, L.T, Wu, M.C, Chang, H.Y, Chen, N.C, Lin, C.C, Chuankhayan, P, Huang, Y.C, Lin, P.J, Chen, C.J. | 登録日 | 2020-05-04 | 公開日 | 2020-11-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural insights into the histidine-containing phospho-transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory system in Pseudomonas aeruginosa Iucrj, 7, 2020
|
|
6MGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mgk by Molmil](/molmil-images/mine/6mgk) | Crystal structure of the catalytic domain from GH74 enzyme PoGH74 from Paenibacillus odorifer, in complex with XLX xyloglucan | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Stogios, P.J, Skarina, T, Nocek, B, Arnal, G, Brumer, H, Savchenko, A. | 登録日 | 2018-09-14 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74endo-xyloglucanase. Biochem. J., 475, 2018
|
|
6MIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mij by Molmil](/molmil-images/mine/6mij) | Crystal structure of EF-Tu from Acinetobacter baumannii in complex with Mg2+ and GDP | 分子名称: | Elongation factor Tu, FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-09-19 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | 主引用文献 | To be published To Be Published
|
|
8GJZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gjz by Molmil](/molmil-images/mine/8gjz) | Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA | 分子名称: | 2'3'-cUA, Stimulator of interferon genes protein | 著者 | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | 登録日 | 2023-03-16 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
5NMH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nmh by Molmil](/molmil-images/mine/5nmh) | HLA A02 presenting SLYNTIATL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2017-04-05 | 公開日 | 2017-11-15 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
|
|
4YND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ynd by Molmil](/molmil-images/mine/4ynd) | The Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2 | 分子名称: | N-cyclohexyl-N~3~-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | 著者 | Sweis, R.F, Wang, Z, Algire, M, Arrowsmith, C.H, Brown, P.J, Chiang, G.C, Guo, J, Jakob, C.G, Kennedy, S, Li, F, Soni, N.B, Vedadi, M, Pappano, W.N. | 登録日 | 2015-03-09 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2. Acs Med.Chem.Lett., 6, 2015
|
|
6PTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pta by Molmil](/molmil-images/mine/6pta) | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP | 分子名称: | ADP-ribosylation factor, GUANOSINE-5'-DIPHOSPHATE | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-07-15 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP To Be Published
|
|
5NPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5npz by Molmil](/molmil-images/mine/5npz) | Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting EFEDLTFLA | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-05-02 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
|
|
7A2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7a2d by Molmil](/molmil-images/mine/7a2d) | Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation to the cell division site | 分子名称: | Uncharacterized protein YraP | 著者 | Bryant, J.A, Morris, F.C, Knowles, T.J, Maderbocus, R, Heinz, E, Boelter, G, Alodaini, D, Colyer, A, Wotherspoon, P.J, Staunton, K.A, Jeeves, M, Browning, D.F, Sevastsyanovich, Y.R, Wells, T.J, Rossiter, A.E, Bavro, V.N, Sridhar, P, Ward, D.G, Chong, Z.S, Goodall, E.C.A, Icke, C, Teo, A, Chng, S.S, Roper, D.I, Lithgow, T, Cunningham, A.F, Banzhaf, M, Overduin, M, Henderson, I.R. | 登録日 | 2020-08-17 | 公開日 | 2020-12-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation. Elife, 9, 2020
|
|
7TQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tqn by Molmil](/molmil-images/mine/7tqn) | |
7TQQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tqq by Molmil](/molmil-images/mine/7tqq) | |
7TQO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tqo by Molmil](/molmil-images/mine/7tqo) | |