8GBE

Structure of a viral gasdermin protein A47 from Eptesipox virus

Summary for 8GBE

Entry DOI	10.2210/pdb8gbe/pdb
Descriptor	Protein A47 (2 entities in total)
Functional Keywords	viral mimicry, gasdermin, caspase, autoinhibition, pyroptosis, bats, immunity, cell death, immune system, viral protein
Biological source	Eptesipox virus
Total number of polymer chains	1
Total formula weight	23802.73
Authors	Johnson, A.G.,Kranzusch, P.J. (deposition date: 2023-02-25, release date: 2023-03-15, Last modification date: 2023-03-22)
Primary citation	Boys, I.N.,Johnson, A.G.,Quinlan, M.,Kranzusch, P.J.,Elde, N.C. Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses. Biorxiv, 2023 Cited by PubMed: 36909515 DOI: 10.1101/2023.02.26.529821 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation