8GJZ

Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA

Summary for 8GJZ

• Entry DOI: 10.2210/pdb8gjz/pdb
• Related: 8EFM
• Descriptor: Stimulator of interferon genes protein, 2'3'-cUA (3 entities in total)
• Functional Keywords: sting, cyclic dinucleotide, innate immunity, cgas, immune system
• Biological source: Stylophora pistillata
• Total number of polymer chains: 2
• Total formula weight: 44345.29

Authors

Li, Y.,Toyoda, H.,Slavik, K.M.,Morehouse, B.R.,Kranzusch, P.J. (deposition date: 2023-03-16, release date: 2023-07-05, Last modification date: 2023-08-02)

• Primary citation: Li, Y.,Slavik, K.M.,Toyoda, H.C.,Morehouse, B.R.,de Oliveira Mann, C.C.,Elek, A.,Levy, S.,Wang, Z.,Mears, K.S.,Liu, J.,Kashin, D.,Guo, X.,Mass, T.,Sebe-Pedros, A.,Schwede, F.,Kranzusch, P.J.; cGLRs are a diverse family of pattern recognition receptors in innate immunity.; Cell, 186:3261-3276.e20, 2023; PubMed: 37379839; DOI: 10.1016/j.cell.2023.05.038

Experimental method

X-RAY DIFFRACTION (2.92 Å)