7TQO

Structure of human TREX1

Summary for 7TQO

Entry DOI	10.2210/pdb7tqo/pdb
Descriptor	Three-prime repair exonuclease 1 (2 entities in total)
Functional Keywords	nuclease, dnase, innate immunity, autoimmunity, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	26096.93
Authors	Zhou, W.,Richmond-Buccola, D.,Kranzusch, P.J. (deposition date: 2022-01-26, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citation	Zhou, W.,Richmond-Buccola, D.,Wang, Q.,Kranzusch, P.J. Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13:4277-4277, 2022 Cited by PubMed: 35879334 DOI: 10.1038/s41467-022-32055-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation