7SFQ

EmrE S64V Mutant Bound to tetra(4-fluorophenyl)phosphonium at pH 8.0

Summary for 7SFQ

Entry DOI	10.2210/pdb7sfq/pdb
NMR Information	BMRB: 30957
Descriptor	Multidrug transporter EmrE, tetrakis(4-fluorophenyl)phosphanium (2 entities in total)
Functional Keywords	multidrug resistance protein, smr transporter, efflux protein, proton-coupled, membrane protein
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	24362.01
Authors	Shcherbakov, A.A.,Spreacker, P.J.,Dregni, A.J.,Henzler-Wildman, K.A.,Hong, M. (deposition date: 2021-10-04, release date: 2022-03-02, Last modification date: 2024-05-15)
Primary citation	Shcherbakov, A.A.,Spreacker, P.J.,Dregni, A.J.,Henzler-Wildman, K.A.,Hong, M. High-pH structure of EmrE reveals the mechanism of proton-coupled substrate transport. Nat Commun, 13:991-991, 2022 Cited by PubMed: 35181664 DOI: 10.1038/s41467-022-28556-6 PDB entries with the same primary citation
Experimental method	SOLID-STATE NMR

Structure validation