5MHA
D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with a mixture of 2-ketohexanoic acid and 2-hydroxyhexanoic acid, and NADPH (1.57 A resolution)
Summary for 5MHA
Entry DOI | 10.2210/pdb5mha/pdb |
Related | 5MH5 5MH6 |
Descriptor | D-2-hydroxyacid dehydrogenase, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | d-2-hydroxyacid dehydrogenase, halophile, chiral specificity, reaction mechanism, oxidoreductase |
Biological source | Haloferax mediterranei ATCC 33500 |
Total number of polymer chains | 2 |
Total formula weight | 69382.01 |
Authors | Bisson, C.,Baker, P.J.,Domenech Perez, J.,Pramanpol, N.,Harding, S.E.,Rice, D.W.,Ferrer, J. (deposition date: 2016-11-23, release date: 2018-05-09, Last modification date: 2024-06-19) |
Primary citation | Domenech Perez, J.,Pramanpol, N.,Baker, P.J.,Bisson, C.,Harding, S.E.,Rice, D.W.,Ferrer, J. Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
Download full validation report