5MH5

D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-keto-hexanoic acid and NADP+ (1.4 A resolution)

Summary for 5MH5

• Entry DOI: 10.2210/pdb5mh5/pdb
• Descriptor: D-2-hydroxyacid dehydrogenase, MAGNESIUM ION, 2-Ketohexanoic acid, ... (6 entities in total)
• Functional Keywords: d-2-hydroxyacid dehydrogenase, halophile, chiral specificity, reaction mechanism, oxidoreductase
• Biological source: Haloferax mediterranei ATCC 33500
• Total number of polymer chains: 2
• Total formula weight: 69185.61

Authors

Bisson, C.,Baker, P.J.,Domenech Perez, J.,Pramanpol, N.,Harding, S.E.,Rice, D.W.,Ferrer, J. (deposition date: 2016-11-23, release date: 2018-05-02, Last modification date: 2024-02-14)

• Primary citation: Domenech Perez, J.,Pramanpol, N.,Baker, P.J.,Bisson, C.,Harding, S.E.,Rice, D.W.,Ferrer, J.; Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)