5MH5
D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-keto-hexanoic acid and NADP+ (1.4 A resolution)
Summary for 5MH5
Entry DOI | 10.2210/pdb5mh5/pdb |
Descriptor | D-2-hydroxyacid dehydrogenase, MAGNESIUM ION, 2-Ketohexanoic acid, ... (6 entities in total) |
Functional Keywords | d-2-hydroxyacid dehydrogenase, halophile, chiral specificity, reaction mechanism, oxidoreductase |
Biological source | Haloferax mediterranei ATCC 33500 |
Total number of polymer chains | 2 |
Total formula weight | 69185.61 |
Authors | Bisson, C.,Baker, P.J.,Domenech Perez, J.,Pramanpol, N.,Harding, S.E.,Rice, D.W.,Ferrer, J. (deposition date: 2016-11-23, release date: 2018-05-02, Last modification date: 2024-02-14) |
Primary citation | Domenech Perez, J.,Pramanpol, N.,Baker, P.J.,Bisson, C.,Harding, S.E.,Rice, D.W.,Ferrer, J. Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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